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Measurement of the skin urocanic acid content in normal and histidinemic infants (1983)

Yokoya, S. ; Tokuhiro, E. ; Suwa, S. ; [et al.]

Springer

European journal of pediatrics 140 (1983), S. 330-332

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ISSN: 1432-1076

Keywords: Histidinemia ; Urocanic acid ; Histidase

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The urocanic acid content of the skin was measured photometrically in a large number of normal and histidinemic infants. A very high content was demonstrated in the normal newborn infants, followed by a rapid decrease throughout early infancy. In contrast, 36 measurements in 17 infants with histidinemia revealed a much lower content even in their newborn periods. Thus, the quantification of skin urocanic acid was considered to be simple and useful for confirming the diagnosis of histidinemia, especially in a neonatal mass-screening program.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00442675

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