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  • Vitamin B12  (2)
  • Adenylate cyclase kinetics  (1)
  • Amino acid transport  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Distinct effects of the C-terminal octapeptide of cholecystokinin and of a cholera toxin pretreatment on the kinetics of rat pancreatic adenylate cyclase activity
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/General Subjects 675 (1981), S. 46-61 
    Details
    ISSN: 0304-4165
    Schlagwort(e): (Rat pancreas) ; Adenylate cyclase kinetics ; C-terminal octapeptide ; Cholecystokinin ; Cholera toxin ; Guanine nucleotide
    Quelle: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Thema: Biologie , Chemie und Pharmazie , Medizin , Physik
    Materialart: Digitale Medien
    URL: http://linkinghub.elsevier.com/retrieve/pii/0304-4165(81)90068-4
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Cerebral vascular complication and hyperhomocysteinemia in a cystinotic uremic child (1999)
    Springer
    Pediatric nephrology 13 (1999), S. 73-76 
    Details
    ISSN: 1432-198X
    Schlagwort(e): Key words Uremia ; Homocysteine ; Cerebrovascular disease ; Thermolabile methylenetetrahydrofolate reductase variant ; Cystinosis ; Folic acid ; Vitamin B12
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract  We report a 13-year-old girl with nephropathic cystinosis on chronic peritoneal dialysis who presented with two episodes of stroke. Laboratory evaluation showed severe hyperhomocysteinemia (108 µmol/l). Further testing revealed that she was homozygous for the thermolabile variant of the methylenetetrahydrofolate reductase (MTHFR) gene. Treatment with folic acid and vitamin B12 lowered plasma homocysteine to less than 20 µmol/l. No further episodes of stroke occurred over a follow-up of 12 months. Homocysteine levels should be measured in patients with chronic renal failure, since simple and safe treatment with folic acid and vitamin B12 is effective in lowering the plasma homocysteine level in patients with the thermolabile MTHFR allele.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004670050567
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  • 3
    Digitale Medien
    Digitale Medien
    Nutritional vitamin B12 deficiency: Two cases detected by routine newborn urinary screening (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 218-220 
    Details
    ISSN: 1432-1076
    Schlagwort(e): Vitamin B12 ; Methylmalonic aciduria ; Newborn screening ; Cobalamin
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We describe two asymptomatic newborns with nutritional vitamin B12 deficiency in whom increased urinary methylmalonic acid was detected by routine neonatal screening at 3 weeks of age. Both infants were exclusively breast-fed. One mother suffered from pernicious anaemia, and the other was a strict vegetarian. Both mothers had no clinical or haematological abnormality, aside from a borderline mean corpuscular volume for the vegetarian mother. This report illustrates the early appearance of functional vitamin B12 deficiency in breastfed infants of vitamin B12-depleted mothers. It also demonstrates that urinary methylmalonic acid measurement is a sensitive indicator of tissue vitamin B12 deficiency.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01954389
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  • 4
    Digitale Medien
    Digitale Medien
    Genetic control of lysine permeases in Saccharomycopsis lipolytica (1979)
    Springer
    Archives of microbiology 122 (1979), S. 201-205 
    Details
    ISSN: 1432-072X
    Schlagwort(e): Amino acid transport ; Yeast genetics ; Multiple drug resistance
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract In order to obtain strains of Saccharomycopsis lipolytica impaired in the active transport of l-lysine, mutants resistant to a mixture of l-canavanine, l-4-5-transdehydrolysine and l-S-amino ethylcysteine, taken either all three or two by two, were isolated. These compounds were shown previously to be competitive inhibitors of l-lysine uptake. The resistance patterns and excretion capacity of the mutants were established. All mutants behaved as monogenic. Recombination tests indicated that four genes at least were involved. All mutants were impaired in both high and low affinity l-lysine transport systems. Several hypotheses on the functions of these genes are put forward and discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00411361
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