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  • 1
    ISSN: 1432-2072
    Keywords: Key words Sumatriptan ; Food intake ; Plasma growth hormone ; Women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied the effect of the 5-HT1B/1D receptor agonist sumatriptan (6 mg SC) on plasma growth hormone and prolactin and food intake in 15 healthy female subjects using a double-blind, placebo-controlled, cross-over design. Sumatriptan significantly elevated plasma growth hormone but did not alter plasma prolactin. Sumatriptan also significantly lowered total food intake in a buffet meal, particularly decreasing the intake of fat. Our results indicate that 5-HT1B/1D receptors may be involved in the regulation of food intake in humans. In addition, while activation of 5-HT1B/1D receptors stimulates growth hormone release in both men and women, sumatriptan lowers plasma prolactin only in men, suggesting sex differences in the 5-HT regulation of prolactin release.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 50 (1982), S. 133-144 
    ISSN: 1439-6327
    Keywords: Fatigue ; Oxygen uptake ; Isometric and rhythmic exercise ; Women ; Lifting exercise
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Physiological responses were measured in 7 women subjects who lifted boxes weighing 6.8, 15.9 or 22.7 kg from the floor to a height of 60 cm. After training and establishing the $$\dot V$$ O2 max, the boxes were lifted for 1 h at 30, 50, and 60% $$\dot V$$ O2 max. The changes in heart rate, $$\dot V$$ O2, the integrated EMG during lifting and the loss of isometric hand-grip endurance after lifting were used to assess the development of fatigue. There was no evidence of fatigue at 30% $$\dot V$$ O2 max but fatigue did exist in some conditions at 50% and in all conditions at 60% $$\dot V$$ O2 max. It is suggested that fatigue is unlikely to occur while lifting boxes up to 15.9 kg weight at 35–40% $$\dot V$$ O2 max, i.e., at rates of lifting varying from 5 to 7 times per min.
    Type of Medium: Electronic Resource
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