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  • 1
    Electronic Resource
    Electronic Resource
    Acid-induced esophagitis in cats is prevented by sucralfate but not synthetic prostaglandin E (1988)
    Springer
    Digestive diseases and sciences 33 (1988), S. 217-224 
    Details
    ISSN: 1573-2568
    Keywords: esophagitis ; sucralfate ; prostaglandin ; cytoprotection ; acid
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The cytoprotective effects of liquid sucralfate and a synthetic analog of prostaglandin E1 (PGE1) on acid-induced esophagitis in cats were studied. Esophagitis was induced in adult cats using a constant infusion of 0.1 N HCl at 1 ml/min for 20 min. Animals were infused for either one or three days. Mucosal lesions were evaluated by blinded investigators using both fiberoptic endoscopy and light microscopy. Histologic changes included basal cell hyperplasia, intraepithelial leukocytosis, and subepithelial leukocytosis. Liquid sucralfate given prior to acid infusion consistently prevented acid-induced lesions in both one- and three-day infusions, demonstrated by both endoscopy and quantitative histologic scoring. Indomethacin (200 μg/kg) given prior to sucralfate and acid did not affect sucralfate cytoprotection. Synthetic PGE1, given in doses of 5 μg/kg and 100 μg/kg, afforded no esophageal cytoprotection. These studies indicate that sucralfate is cytoprotective against acid-induced esophageal injury in cats, an effect that does not appear to be mediated by prostaglandin. In addition, synthetic PGE1 does not confer protection in this animal model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01535736
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  • 2
    Electronic Resource
    Electronic Resource
    Experimental and theoretical investigation of extrudate swell of polymer melts from small (length)/(cross-section) ratio slit and capillary dies (1980)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 20 (1980), S. 182-189 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: An experimental and theoretical study is presented of extrudate swell from short capillary and slit dies. The polymer melts studied were polystyrene and polypropylene. The swell from slit dies is greater than the swell from capillaries. Decreasing die entry angle for capillary dies decreases swell. The argument is made that elongational How existing in the die entry region and for short dies determines extrudate swell. Dimensional analysis arguments are used to relate extrudate swell to a Weissenberg number based on elongational flow at the die entrance and the detailed die geometry. Correlations are developed. The theoretical study is based on unconstrained elastic recovery following elongational How through the die entrance region.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760200303
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Extrudate swell and extrusion pressure loss of polymer melts flowing through rectangular and trapezoidal dies (1981)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 21 (1981), S. 1101-1107 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A theoretical and experimental study of pressure losses and extrudate swell of flow through dies with complex crosssections is presented. The range of utility of models based on one-dimensional shearing on pressure loss-extrusion rate behavior is indicated. A procedure to predict extrudate profiles emerging from complex dies is developed. This is based on consideration of the idea of unconstrained elastic recovery from long dies. The theoretical predictions are contrasted with experiments on polystyrene and polypropylene.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760211609
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Extrudate swell from slit and capillary dies: An experimental and theoretical study (1979)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 19 (1979), S. 609-616 
    Details
    ISSN: 0032-3888
    Keywords: Chemistry ; Chemical Engineering
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: A comparative experimental study of extrudate swell from long slit and capillary dies is reported for rheologically characterized polystyrene and polypropylene melts. Generally extrudate swell from a slit is greater than that from a capillary die. At low die wall shear rates it goes to a value of about 1.2 as opposed to about 1.1 found for capillary dies. The onset and character of extrudate distortion have been studied. The experimental results are compared with theories of swell based on unconstrained recovery from Poiseuille flow in these geometries. A detailed analysis of such theories of extrudate swell based on the original work of Tanner has been carried out. The analysis is placed in a more general form which should be valid for a range of die cross-sections.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/pen.760190904
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    Paper (German National Licenses)
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