ISSN:
1573-8221
Keywords:
adrenal cortex
;
hypoxia
;
nandrolone
;
morphology
;
stereology
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Acute hypoxia has a pronounced catabolic effect, whereas repeated hypoxic episodes promote hypertrophy of the adrenal cortex. Steroid hyperproduction caused by stress reaction after single hypoxic episode persists after repeated hypoxic episodes. The relations between vessels and parenchyma play the key role in spatial reorganization of the adrenal cortex. Increased volume and surface-volume ratios between sinusoids and adrenocorticocytes point to the enhancement of transcapillary exchange and can be regarded as an adaptive compensatory reaction on the tissue level. Nandrolone decreases antianabolic and stress effects of hypoxia, thus potentiating compensatory adaptive reactions both after single and repeated hypoxic episodes.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02433336
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