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Digitale Medien

Root squaring using level-index arithmetic (1989)

Clenshaw, C. W. ; Turner, P. R.

Springer

Computing 43 (1989), S. 171-185

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ISSN: 1436-5057

Schlagwort(e): 65G99 ; 65H05 ; Level-index ; symmetric level-index ; root-squaring ; polynomial equations

Quelle: Springer Online Journal Archives 1860-2000

Thema: Informatik

Beschreibung / Inhaltsverzeichnis: Zusammenfassung Das “symmetrische Höhenindexsystem” (sli) zur Zahlendarstellung vereinfacht die Überwachung der Rechengenauigkeit und vermeidet overflow—oder underflow—Probleme. In dieser Arbeit werden die praktischen Vorzüge des Systems am Beispiel des Graeffeverfahrens vorgeführt.

Notizen: Abstract The symmetric level-index,sli, system for representing numbers eases the monitoring of precision while avoiding the problems associated with overflow and underflow. In this paper the practical benefits of the system are displayed, using the root-squaring method of Graeffe as a vehicle.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02241860

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Digitale Medien

The relationship between theophylline clearance and age in adult life (1989)

Jackson, S. H. D. ; Johnston, A. ; Woollard, R. ; [weitere]

Springer

European journal of clinical pharmacology 36 (1989), S. 29-34

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ISSN: 1432-1041

Schlagwort(e): theophylline ; asthma ; clearance ; age ; adults ; elderly ; normal subjects

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary Fifty three subjects (31 normal volunteers and 22 patients with asthma) between the ages of 20 and 87 years had their theophylline clearance measured. Volume of distribution (V) and terminal elimination half-life (t1/2) were also calculated in the volunteers who received i.v. theophylline. Although patients tended to have higher clearance values than volunteers, in both groups the oldest third had the lowest clearances. For the combined group (corrected for the patient effect) the oldest third (mean age 70 years) had a mean clearance of 0.53 versus 0.72 for the middle third (mean age 47 years) and 0.73 ml/min/kg CBW for the youngest third (mean age 26 years). There was no statistically significant age related change in V/kg CBW but t1/2 did rise with increasing age. Thus, although clearance does not fall with increasing age during younger adult life, there is a fall during late adult life becoming apparent in the seventh, eighth and ninth decades.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00561019

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