ISSN:
1420-9071
Keywords:
Δ1-tetrahydrocannabinol
;
metabolites
;
antagonists
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The results described here demonstrate that THC-induced catalepsy in mice can be substantially inhibited by the prior administration of Δ1-THC-7-oic acid, the major metabolite of THC in most species including humans. This raises the possibility that the intensity and duration of action of THC may depend to a large degree on the levels of this metabolite at the sites of action.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01940427
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