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  • 1
    Electronic Resource
    Electronic Resource
    Flupirtine maleate and antipyrine half-life (1987)
    Springer
    European journal of clinical pharmacology 33 (1987), S. 437-437 
    Details
    ISSN: 1432-1041
    Keywords: Flupirtine maleate ; antipyrine ; half-life ; pharmaco kinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00637646
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    An examination of a possible pharmacokinetic interaction between nifedipine and antipyrine (1990)
    Springer
    European journal of clinical pharmacology 39 (1990), S. 405-407 
    Details
    ISSN: 1432-1041
    Keywords: Nifedipine ; antipyrine ; interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The influence of 2 weeks oral intake of nifedipine (2×20 mg) on the oxidative metabolism of antipyrine was investigated in 12 normal volunteers, who had 1050 mg antipyrine solution orally before and after the course of nifedipine. There were no statistically significant differences in the saliva pharmacokinetic parameters of antipyrine on both occasions. However, the metabolite profile of antipyrine in urine showed a significant reduction in the amount of norantipyrine excreted after compared to that before nifedipine administration (16.5 vs 19.6%). This may have implications for drugs that share a similar demethylation pathway with norantipyrine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00315420
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Direct-prediction quasi-Newton methods in Hilbert space with applications to control problems (1977)
    Springer
    Journal of optimization theory and applications 21 (1977), S. 199-211 
    Details
    ISSN: 1573-2878
    Keywords: Variable-metric methods ; optimization theorems ; Hilbert spaces ; control theory
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this paper, the Hilbert-space analogue of a result of Huang, that all the methods in the Huang class generate the same sequence of points when applied to a quadratic functional with exact linear searches, is established. The convergence of a class of direct prediction methods based on some work of Dixon is then proved, and these methods are then applied to some control problems. Their performance is found to be comparable with methods involving exact linear searches.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00932520
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Direct prediction methods in Hilbert space with applications to control problems (1977)
    Springer
    Journal of optimization theory and applications 22 (1977), S. 399-415 
    Details
    ISSN: 1573-2878
    Keywords: Variable-metric methods ; optimization theorems ; Hilbert spaces ; control theory
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this paper, the convergence of variable-metric methods without line searches (direct prediction methods) applied to quadratic functionals on a Hilbert space is established. The methods are then applied to certain control problems with both free endpoints and fixed endpoints. Computational results are reported and compared with earlier results. The methods discussed here are found to compare favorably with earlier methods involving line searches and with other direct prediction quasi-Newton methods.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00932863
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    Paper (German National Licenses)
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