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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Clinical autonomic research 7 (1997), S. 5-11 
    ISSN: 1619-1560
    Keywords: sympathetic ; vasoconstrictor reflexes ; autonomic dysfunction ; Parkinson's disease ; levodopa treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Centrally and locally elicited sympathetic vasoconstrictor responses were examined in 12 patients with symptoms and signs of cardiovascular autonomic dysfunction due to Parkinson's disease. The sympathetic reflex mechanisms were measured in skeletal muscle and subcutaneous tissue of the arm and leg using the 133-Xenon washout technique. This method allows differentiation between local and central sympathetic reflexes in different tissues. The results indicate an abolished centrally mediated vasoconstrictor response in skeletal muscle in the arm and a decreased response in skeletal muscle in the leg and in subcutaneous tissue. This is in agreement with an autonomic dysfunction located in the central nervous system. A possible spinal sympathetic reflex controlling blood flow in subcutaneous tissue and leg muscles is considered. The sympathetic vasoconstrictor responses in parkinsonian patients without autonomic failure were of normal magnitude and the responses were not affected by long-term levodopa treatment.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 46 (1981), S. 379-386 
    ISSN: 1439-6327
    Keywords: Heart rate ; Maximal heart rate ; Ventilatory frequency ; Dimensional dependency ; Allometric expressions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Heart rate (HR) and ventilatory frequency (f) were determined at rest in 79 boys and 91 girls aged 0.07–20 years and with a range in heights from 54–198 cm to establish the relationship between decrease in HR and f during early life with increase in body dimensions. From theoretical considerations it is assumed that frequencies such as HR and f are proportional to a characteristic linear dimension of the subjects in minus first power (≂ θ−1). In the present material resting HR and f decreased with increasing height of the subjects according to the equations HR=6,408·height−0.9015 (r=0.8983) and f=5,969·height−1.1691 (r=0.8471). These results suggest that the decrease in resting HR and f during childhood and adolescence corresponds well with increase in body dimensions. A similar equation was developed for HRmax within the range of heights from 149–198 cm. Only a slight dependency on height was observed (HRmax=θ−0.1642, r=0.3796).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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