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  • 1
    Digitale Medien
    Digitale Medien
    196. Behandlung begleitender Gefäßverletzungen bei Unfallen (1974)
    Springer
    Langenbeck's archives of surgery 337 (1974), S. 849-849 
    Details
    ISSN: 1435-2451
    Schlagwort(e): Vascular Injury ; Arterial Reconstruction ; Traumatic Ischemia ; Gefäßverletzung ; Arterienrekonstruktion ; Traumatisch bedingteIschämie
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Bericht über 314 Eingriffe am Arteriensystem nach Unfällen, davon 35 Aortenverletzungen. Unfallursachen: penetrierende, iatrogene, stumpfe Verletzungen, Verkehrsunfälle. Therapie: primär 40 Ligaturen, 9 Amputationen, 19 mal konservative Behandlung. 246 Arterien warden rekonstruiert. Ergebnis: 183 Rekonstruktionen zeigen gute, 18 eingeschränkte Funktion, 24 Patienten warden amputiert, 31 starben. — 28 Ligaturen zeigen gute Funktion, 5 schlechte Funktion, 6 Patienten warden amputiert, 1 starb. — Die konservativ Behandelten zeigen 9 mal gute, 5 mal eingeschränkte Funktion, 1 Amputation und 3 mal letalen Ausgang.
    Notizen: Summary The report deals with 314 vascular operations after accidents, 35 of which involved aortic injury. Etiology: penetrating, iatrogennc, traumatic, following traffic accidents. Treatment: primary ligations in 40, amputation in 9, conservative treatment in 19 patients. Arterial reconstruction was performed in 246 cases. Results: 183 reconstructions resulted in good, 18 in limited function, 24 patients needed amputation, and 31 died. Twenty-eight ligations left good and 5 bad function, 6 patients needed amputation, and 1 died. Of the conservatively treated patients, 9 had good, and 5 had limited function, 1 required amputation, and 3 died.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01278828
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  • 2
    Digitale Medien
    Digitale Medien
    The distribution of Lewy bodies in pure autonomic failure: autopsy findings and review of the literature (1997)
    Springer
    Acta neuropathologica 94 (1997), S. 192-196 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Key words Pure autonomic failure ; Lewy bodies ; Autopsy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Pure autonomic failure (PAF; also known as idiopathic orthostatic hypotension or Bradbury-Eggleston syndrome) is an uncommon sporadic disorder, characterized by autonomic failure without other neurological deficits and histopathologically by cell loss in intermediolateral columns and sympathetic ganglia. Few postmortem studies of patients with PAF have been reported in the literature, and none have demonstrated Lewy bodies in distal axons, although this has been described as a feature in Parkinson’s disease with autonomic failure. We report a patient with PAF who had orthostatic hypotension and urinary symptoms for 15 years prior to death at the age of 63 years. Postmortem findings included typical and atypical Lewy bodies in the substantia nigra, locus ceruleus, substantia innominata, and sympathetic ganglia, as well as in autonomic axons in the epicardial fat, autonomic nerve fascicles in periadrenal adipose tissue, and autonomic nerves in the muscularis of the urinary bladder. Sites of autonomic nerve involvement correlated with clinical symptomatology, and thus were a valuable observation in the complete autopsy. Systemic autopsy results should be reviewed carefully in patients with PAF, as Lewy bodies in this disease may be seen in distal axons at a great length from their primary cell bodies.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s004010050693
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  • 3
    Digitale Medien
    Digitale Medien
    Effect of recombinant erythropoietin on anemia and orthostatic hypotension in primary autonomic failure (1995)
    Springer
    Clinical autonomic research 5 (1995), S. 211-213 
    Details
    ISSN: 1619-1560
    Schlagwort(e): erythropoietin ; orthostatic hypotension ; autonomic failure ; anemia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Anemia is a common complication of autonomic failure and reduced red blood cell mass may contribute to the orthostatic hypotension of these patients. We investigated whether treatment with recombinant erythropoietin improves anemia and increases blood pressure in patients with primary autonomic failure. Three patients with multiple system atrophy and autonomic failure and one with pure autonomic failure were studied. All patients had normocytic normochromic anemia and low (n = 2) or normal (n = 2) serum levels of erythropoietin. Treatment with erythropoietin, 4000 U subcutaneously biweekly for 6 weeks, increased hematocrit and blood pressure in all patients. Hematocrit increased from 33.9 ± 0.7 to 44.3 ± 1.4%, blood pressure in supine position increased from 150 ± 8/87 ± 8 (systolic/diastolic; mean ± SD) to 166 ± 25/92 ± 12 mmHg, and after 3 min in the head-up tilt position from 86 ± 21/47 ± 15 to 102 ± 23/63 ± 12 mmHg, (p 〈 0.05). All patients reported improvement in orthostatic symptoms and increased tolerance to standing. The study shows that treatment with erythropoietin improves anemia, increases blood pressure and ameliorates orthostatic hypotension in patients with primary autonomic failure.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01824009
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  • 4
    Digitale Medien
    Digitale Medien
    Differential effect of L-threo-3,4-dihydroxyphenylserine in pure autonomic failure and multiple system atrophy with autonomic failure (1991)
    Springer
    Journal of neural transmission 3 (1991), S. 143-148 
    Details
    ISSN: 1435-1463
    Schlagwort(e): 3,4-Dihydroxyphenylserine ; blood pressure ; orthostatic hypotension ; autonomic failure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Treatment with L-threo-3,4-dihydroxyphenylserine (L-threo-dops), a synthetic precursor of norepinephrine, significantly increased upright blood pressure in patients with multiple system atrophy but had no effect on the upright blood pressure of patients with pure autonomic failure. These results suggest that the site of action of L-threo-dops is central and that its pressor effect requires intact peripheral sympathetic neurons.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF02260889
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