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Digitale Medien

The effect of alinidine (St 567) on emotionally induced tachycardia in man (1982)

Auböck, J. ; Konzett, H. ; Olbrich, E.

Springer

European journal of clinical pharmacology 21 (1982), S. 467-471

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Details

ISSN: 1432-1041

Schlagwort(e): alinidine ; emotional stress ; tachycardia ; healthy volunteers ; heart rate ; blood pressure ; forearm blood flow ; St 567

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie , Medizin

Notizen: Summary Experiments were performed in a randomized double blind cross-over study in 6 healthy volunteers to answer the question if alinidine, a new analogue of clonidine with a bradycardic effect directly on the sinus node, would have an effect on an emotionally — induced tachycardia. Alinidine 40 mg orally significantly (1%) reduced the tachycardia and the concomitant rise in diastolic blood pressure during the stress of performing a mental task. Forearm blood flow and the efficiency (total score in the mental task) remained unchanged by alinidine.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00542040

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