ISSN:
1573-7373
Keywords:
brain tumor oncology
;
glioblastoma multiforme
;
hyperthermia
;
radiation therapy
;
ultrasound
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Hyperthermia delivered by scanned focused ultrasound was combined with external beam radiation to treat 15 patients with primary malignant tumors of the brain. A preliminary craniectomy was performed to avoid attenuation of the ultrasound beam by the skull, and multiple thermal sensors were employed to ascertain intratumoral temperatures. The target temperature was 42.5°C at the tumor boundary. This was attained at more than one point during every complete treatment, while a mean temperature in excess of 42°C was achieved within the scanned tumor volume during at least 1 treatment in 11 patients. Technical problems and toxicities are described.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00177540
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