ISSN:
1573-8221
Keywords:
myocardial ischemia
;
cardiac arrhythmias
;
ventricular fibrillation
;
laser irradiation
;
sympathetic cardiac regulation
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The role of sympathetic nervous system in the antiarrhythmic effect of intra-atrial laser irradiation (λ=632.8 nm) during myocardial ischemia was studied in acute experiments on Nembutal-anesthetized cats. Laser irradiation applied after bilateral, dextral, or sinistral transection of cardiac branches of stellate ganglia increased the number of ischemic rhythm disturbances that developed after occlusion of the circumflex branch of the left coronary artery. The maximum increase in the number of arrhythmias was observed after dextral transection, the occurrence of ventricular fibrillation being 100%. Bilateral transection provoked a larger number of ischemic rhythm disturbances than the sinistral transection. It is probable that the development of the antiarrhythmic effect of laser irradiation requires sustained sympathetic activity targeted at the nonischemic regions in the myocardium that could play a stabilizing role during local ischemic damage to the heart.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02447246
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