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  • 1
    ISSN: 0935-6304
    Schlagwort(e): Computer modeling of GC ; computer simulation of GC ; computer-assisted GC analysis ; GC multicolumn analysis ; heart cutting GC analysis ; computer-assisted column design ; computer-assisted selectivity tuning ; retention index mapping ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: ---The analysis of four components in a mixture containing many possible interferents is simplified by heart-cutting serially connected columns containing stationary phases of widely different polarities. The design of the proper lengths of the two columns and timing the heart-cuts is accomplished with the aid of a computer simulation of the problem. The computer program calculates the proper lengths of column to produce the shortest analysis time and also outputs the predicted chromatograms from both columns. The chromatogram from the first column is used to construct the timing gates for the heart-cuts and the chromatogram from the second or analytical column is used to set integration gates for the selected compounds of interest.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Weinheim : Wiley-Blackwell
    Journal of High Resolution Chromatography 13 (1990), S. 764-773 
    ISSN: 0935-6304
    Schlagwort(e): Capillary GC ; Computer optimization ; Coupled columns ; Column switching ; Chemistry ; Analytical Chemistry and Spectroscopy
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Clearly, the usefulness of a computer-aided column design program will depend on its ability to predict quickly and accurately, a design which will yield chromatograms closely approximating those obtained experimentally. Such a computer model for designing and specifying operating conditions for optimum performance of either single or serially coupled columns with different stationary phases is described herein. Tests have been performed in order to verify the accuracy of the model.In addition to single column optimization and the design of column combinations which can be used to achieve separations difficult or impossible on a single phase alone, the model has proven quite useful as an aid to the design and development of multicolumn analysis procedures that involve critical timing of valve-switching sequences.
    Zusätzliches Material: 12 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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