ISSN:
1573-8221
Keywords:
contraceptive activity
;
steroid preparations
;
antiadrenergic drugs
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Experiments on sexually mature female rats showed that daily simultaneous administration of mestranol (0.04 mg/kg) and megestrol acetate (0.8 mg/kg) by gastric tube for 14 days had no appreciable contraceptive effect, whereas administration of the steroids in the same doses combined with antiadrenergic drugs α-methyldopa (100 mg/kg) or pyrroxan (10 mg/kg) effectively prevented pregnancy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00832717
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