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  • 1
    Digitale Medien
    Digitale Medien
    Morphological and/or functional imagiology diagnosis of epiphora (1993)
    Springer
    Documenta ophthalmologica 83 (1993), S. 337-348 
    Details
    ISSN: 1573-2622
    Schlagwort(e): Conventional subtraction macrodacryocystopraphy (CSMD) ; Digital subtraction macrodacryocystography (DSMD) ; Epiphora ; Lacrimal ducts (LD) ; Sequential dacryoscyntygraphy (SD)
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Several tests and examinations are necessary for an accurate diagnosis of disorders of the lacrimal drainage system. The AA studied 100 patients with epiphora, divided in two groups. Forty patients, first group (I), aged between 4 and 78 years old (mean age 47.8 ± 9.6 years), were examined using the classical tests for the study of epiphora, sequential dacryoscintigraphy (SD) and conventional subtraction macrodacryocystrography (CSMD). In the second group (II), 60 patients (aged 45.5 ± 8.7 years) were studied using the classical tests and by digital subtraction macrodacryocystography (DSMD). The results showed that when functional epiphora is present, there is no difference between a simple clinical approach and sequential dacryoscintigraphy. However, when information is needed regarding choice of surgical approach, DSMD appears to give the best results.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01204336
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Effect of calcium dobesilate on the blood-retinal barrier in early diabetic retinopathy (1990)
    Springer
    International ophthalmology 14 (1990), S. 81-88 
    Details
    ISSN: 1573-2630
    Schlagwort(e): calcium dobesilate ; diabetic retinopathy ; blood-retinal barrier ; vitreous fluorophotometry ; penetration ratio
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The effect of calcium dobesilate on the alteration of the blood-retinal barrier was studied in 41 adult-onset, non-insulin dependent diabetic patients with minimal or no retinopathy, randomly assigned to receive either oral calcium dobesilate (1000 mg twice daily) or a placebo for 12 months. The posterior vitreous value and the penetration ratio, determined by vitreous fluorophotometry, reflected stabilisation of blood-retinal barrier permeability in the calcium dobesilate patients and deterioration of blood retinal barrier in those given placebo. During the relatively short period of the study, one year, no significant change in microaneurysm and capillary closure gradings was observed. No side effects were associated with calcium dobesilate.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00154206
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Effect of cyclospasmol on early diabetic retinopathy (1987)
    Springer
    International ophthalmology 10 (1987), S. 3-9 
    Details
    ISSN: 1573-2630
    Schlagwort(e): cyclospasmol ; cyclandelate ; diabetic retinopathy ; quantitative vitreous fluorophotometry
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A randomized, double-blind, placebo controlled study to investigate the long-term effect of CyclospasmolR (cyclandelate) on the abnormal permeability of the blood-retinal barrier was performed in 26 patients with insulin-dependent diabetes mellitus for at least 1 year and minimal retinopathy. Cyclospasmol 400 mg or placebo capsules were taken 4 times daily for 12 months by equal numbers in both groups. Each patient underwent a routine ophthalmoscopic examination, retinal fluorescein angiography and quantitative vitreous fluorophotometry to assess the permeability of the blood-retinal barrier just before the trial and following 6 and 12 months of therapy. Laboratory tests for determining blood and urine glucose levels and blood HbA1-levels were also carried out at these assessments. Statistically significant changes in diabetic control, in HbA1-levels or in the frequency of retinal microaneurysms could not be shown in either treatment group during the trial, nor were there any significant differences in these parameters between the two groups. Analysis of fluorophotometric data on fluorescein penetration into the left posterior vitreous demonstrated significant reductions in this parameter during the trial compared to the pretreatment level in Cyclospasmol treated diabetics. These changes in the pretreatment level after 6 and 12 months also differed significantly between the two groups. However, this statistically significant beneficial reduction in fluorescein penetration into the left posterior vitreous did not occur in the right eye in the Cyclospasmol group. In placebo treated patients a consistently deleterious trend for this parameter was observed for both eyes during the one year study. The consistently beneficial trend in the right eye following Cyclospasmol and the consistently deleterious trend in both eyes following placebo with regard to the abnormal permeability of the blood-retinal barrier of diabetics with minimal retinopathy could probably be explained by the small number of patients in both groups. No side-effects were reported.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00202775
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