ISSN:
1435-1463
Keywords:
Locus coeruleus
;
ventral tegmental area
;
6-hydroxydopamine
;
dopamine
;
noradrenaline
;
homovanillic acid
;
dihydroxyphenylacetic acid
;
serotonin
;
5-hydroxyindolacetic acid
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The dopamine (DA) content of the locus coeruleus (LC) and the uptake of tritiated DA in the presence of desmethylimipramine into fresh vibratome sections of the LC-area were determined in control rats and in rats whose ventral tegmental area (VTA) had been destroyed by local application of 6-hydroxydopamine (6-OHDA). Destruction of the VTA reduced the DA content and the number of dopaminergic fibers visualized by radioautography in the LC area. This indicates that the DA containing afferents of the LC originate, at least partly, in the VTA.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01253597
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