ISSN:
1573-8221
Keywords:
Insulin
;
prednisolone
;
glucose reabsorption
;
tubular secretion
;
excretion of sodium by the kidney
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract In experiments on dogs a single injection of insulin in a dose of 1 unit/kg body weight caused an increase in the maximal reabsorption of glucose and secretion of diodone and reduced the excretion of sodium without any change in glomerular filtration. These effects depend on the direct action of insulin, for when it was injected directly into one of the renal arteries its action was manifested only in the kidney on the side of infusion. Prednisolone had no significant effect on glucose and diodone transport when given as a single injection (3–4 mg/kg) or over a period of 10 days (1.5–2 mg/kg daily).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00801820
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