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  • 2000-2004  (1)
  • 1990-1994  (1)
  • colorectal cancer  (1)
  • expert system  (1)
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  • 2000-2004  (1)
  • 1990-1994  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Journal of intelligent manufacturing 2 (1991), S. 261-268 
    ISSN: 1572-8145
    Schlagwort(e): AI ; neural networks ; expert system ; process control
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Maschinenbau
    Notizen: Abstract This paper presents an architecture which combines artificial neural networks (ANNs) and an expert system (ES) into a hybrid, self-improving artificial intelligence (AI) system. The purpose of this project is to explore methods of combining multiple AI technologies into a hybrid intelligent diagnostic and advisory system. ANNs and ESs have different strengths and weaknesses, which can be exploited in such a way that they are complementary to each other: strengths in one system make up for weaknesses in the other, andvice versa. There is, presently, considerable interest in ways to exploit the strengths of these methodologies to produce an intelligent system which is more robust and flexible than one using either technology alone. Any process which involves both data-driven (bottom-up) and concept-driven (top-down) processing is especially well suited to displaying the capabilities of such a hybrid system. The system can take an incoming pattern of signals, as from various points in an automated manufacturing process, and make intelligent process control decisions on the basis of the pattern as preprocessed by the ANNs, with rule-based heuristic help or corroboration from the ES. Patterns of data from the environment which can be classified by either the ES or a human consultant can result in a high-level ANN being created and trained to recognize that pattern on future occurrences. In subsequent cases in which the ANN and the ES fail to agree on a decision concerning the environmental situation, the system can resolve those differences and retrain the networks and/or modify the models of the environment stored in the ES. Work on a hybrid system for perception in machine vision has been funded initially by an Oak Ridge National Laboratory seed grant, and most of the system components are operating presently in a parallel distributed computer environment.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1573-7276
    Schlagwort(e): carcinoembryonic antigen ; circulating tumour cells ; colorectal cancer ; false positive results ; RT-PCR
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract We assessed whether circulating cell positivity using RT-PCR for carcinoembryonic antigen (CEA) cDNA was affected by venesection via a needle compared/with a pre-aspirated venous cannula, and by increased PCR cycles. Systemic blood was sampled by needle and pre-aspirated cannula in 101 healthy individuals with no cancer history. After erythrocyte removal, samples were subjected to RT-PCR using specific primers for CEA, with 29 or 35 RT-PCR cycles. There was a significant difference between the number of subjects whose samples were negative when collected via needle venesection and positive when collected via pre-aspirated cannula, compared with positive by needle venesection and negative by pre-aspirated cannula for both 29 (P=0.016) and 35 (P=0.011) RT-PCR cycles. Venesection technique (P=0.01) and number of cycles (P=0.003) were significant predictors of a positive result. Positive results in healthy subjects were reduced to less than 3% when an aspirated cannula was used for venesection and 〉29 PCR cycles were avoided.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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