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  • 1990-1994  (3)
  • flexible matching  (2)
  • Monoclonal antibody
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Machine learning 8 (1992), S. 5-43 
    ISSN: 0885-6125
    Schlagwort(e): Concept learning ; learning imprecise concepts ; inductive learning ; learning flexible concepts ; two-tiered concept representation ; flexible matching
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract This paper describes a method for learning flexible concepts, by which are meant concepts that lack precise definition and are context-dependent. To describe such concepts, the method employs a two-tiered representation, in which the first tier captures explicitly basic concept properties, and the second tier characterizes allowable concept's modifications and context dependency. In the proposed method, the first tier, called Base Concept Representation (BCR), is created in two phases. In phase 1, the AQ-15 rule learning program is applied to induce a complete and consistent concept description from supplied examples. In phase 2, this description is optimized according to a domain-dependent quality criterion. The second tier, called the inferential concept interpretation (ICI), consists of a procedure for flexible matching, and a set of inference rules. The proposed method has been implemented in the POSEIDON system, and experimentally tested on two real-world problems: learning the concept of an acceptable union contract, and learning voting patterns of Republicans and Democrats in the U.S. Congress. For comparison, a few other learning methods were also applied to the same problems. These methods included simple variants of exemplar-based learning, and an ID-3-type decision tree learning, implemented in the ASSISTANT program. In the experiments, POSEIDON generated concept descriptions that were both, more accurate and also substantially simpler than those produced by the other methods.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Machine learning 8 (1992), S. 5-43 
    ISSN: 0885-6125
    Schlagwort(e): Concept learning ; learning imprecise concepts ; inductive learning ; learning flexible concepts ; two-tiered concept representation ; flexible matching
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract This paper describes a method for learningflexible concepts, by which are meant concepts that lack precise definition and are context-dependent. To describe such concepts, the method employs atwo-tiered representation, in which the first tier captures explicitly basic concept properties, and the second tier characterizes allowable concept's modifications and context dependency. In the proposed method, the first tier, calledBase Concept Representation (BCR), is created in two phases. In phase 1, the AQ-15 rule learning program is applied to induce a complete and consistent concept description from supplied examples. In phase 2, this description is optimized according to a domain-dependent quality criterion. The second tier, called theinferential concept interpretation (ICI), consists of a procedure forflexible matching, and a set of inference rules. The proposed method has been implemented in the POSEIDON system, and experimentally tested on two real-world problems: learning the concept of an acceptable union contract, and learning voting patterns of Republicans and Democrats in the U.S. Congress. For comparison, a few other learning methods were also applied to the same problems. These methods included simple variants of exemplar-based learning, and an ID-3-type decision tree learning, implemented in the ASSISTANT program. In the experiments, POSEIDON generated concept descriptions that were both, more accurate and also substantially simpler than those produced by the other methods.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Molecular Reproduction and Development 27 (1990), S. 152-158 
    ISSN: 1040-452X
    Schlagwort(e): Stallion spermatozoa ; Acrosome reaction ; Monoclonal antibody ; Zona-free hamster eggs ; Life and Medical Sciences ; Cell & Developmental Biology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie
    Notizen: The acrosome of the stallion spermatozoon was visualized by indirect immunofluorescence with monoclonal antibody (18.6) which recognized an integral acrosomal membrane component. Localization was confirmed by electron microscopy using peroxidase labelled antibody. In fresh semen samples (n = 19), 73.9 ± 9.1% of the spermatozoa from five fertile stallions displayed a uniform bright fluorescence over their acrosome region. In two semen samples from an infertile stallion only 28% and 35% of spermatozoa showed the same pattern of fluorescence. Spermatozoa from fertile stallions incubated for up to 12 hours in TALP medium maintained motility and exhibited a significant progressive loss of acrosomes as detected by immunofluorescence. Alternatively, a similar loss of acrosomes could be induced with calcium ionophore A23187 over a 90 minute incubation. Ultrastructural observations and incubation with zona-free hamster eggs indicated that only with ionophore treatment was immunofluorescent acrosome loss correlated with a physiological acrosome reaction, while prolonged sperm incubation led to degenerative membrane changes. It was concluded that, if carefully validated, immunofluorescent localization of the acrosome of stallion sperm with monoclonal antibody could be used to monitor the acrosome reaction. Furthermore, definitive acrosome visualization would be valuable in assessing semen quality.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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