ISSN:
0947-6539
Keywords:
asymmetric synthesis
;
carbene complexes
;
carbohydrates
;
glycosylidenes
;
spiro compounds
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Carbohydrate-modified carbene complexes can be synthesised by combining a sugar electrophile with a metalate nucleophile or vice versa. Acyclic sugar skeletons adopt conformations that are controlled by the minimisation of 1,3-interactions and are not significantly affected by the incorporation of a metal fragment. Thus, the latter can be used exclusively for reactivity tuning. Sugar carbene complexes undergo regio- and stereoselective ligand- and metal-centred reactions such as C2-homologisation and benzannulation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chem.19970031105
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