ISSN:
1573-7381
Keywords:
C.N.S.
;
growth cone
;
dendrite
;
olfactory bulb
;
mouse
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary An improved and simplified method of serial sectioning for electron microscopy was used to prepare material from which were reconstructed dendritic growth cones of mitral cells in neonatal mouse olfactory glomerulus. Growth cones are characterized by: (1) one or more filopodia, each approximately 0.2 μm in diameter, projecting from an expanded dendritic terminal or pre-terminal region; (2) a polygonal array of microfilaments approximately 50 Å in diameter, filling the enlarged terminal and filopodia; (3) an absence of microtubules and a paucity of mitochondria; (4) a few profiles of smooth endoplasmic reticulum or vesicles; (5) occasional axodendritic synapses. These characteristics are compared with those of other growing processes in the nervous system and a consistent picture of the appearance of growing neuronal processes obtained, suitable to use as a guide in a search for additional growing processes in developing and mature brains.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01099183
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