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Digitale Medien

Metal ion-induced permeability changes in cell membranes: A minireview (1994)

Kiss, Tibor ; Osipenko, Oleg

Springer

Cellular and molecular neurobiology 14 (1994), S. 781-789

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ISSN: 1573-6830

Schlagwort(e): excitable membrane ; ionic channel ; heavy metal ; metal ion-induced current

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Summary 1. The paper summarizes the effects of the metal ions Cu2+, Pb2+, Ag+, Hg2+, Zn2+, and Cd2+ applied externally or internally to the surface membrane of different excitable cells. 2. Conductance changes induced by metal ions, and metal ion-activated current, are compared with respect to their ion and voltage dependence. 3. It is suggested that metal ion-induced effects can be realized through special structures of the cell membrane, the metal ion “receptors,” although other mechanisms, as, for example, competition for Ca-binding sites in the channel forming proteins, cannot be excluded.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02088684

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