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Digitale Medien

Endocrine pancreatic control of the release of gastric inhibitory polypeptide (1980)

Dryburgh, Jill R. ; Hampton, S. M. ; Marks, V.

Springer

Diabetologia 19 (1980), S. 397-401

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Details

ISSN: 1432-0428

Schlagwort(e): Gastric inhibitory polypeptide (GIP) ; control of GIP ; intestinal perfusion with fat at GIP ; rat C-peptide ; rat intestine

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Intravenous infusion in anaesthetized rats of rat II C-peptide at a dose which produced circulating levels of 22.8±1.8 nmol/l after 30 min, resulted in a significant reduction (141±7 to 50±4 pmol/1, p〈0.001, mean ± SEM) in the immunoreactive gastric inhibitory polypeptide response to an intestinal perfusion with a fat emulsion. Immunoreactive insulin levels were unchanged from basal in this study. It is suggested that C-peptide must be considered as a candidate for the endocrine pancreatic factor which exerts a negative feedback upon gastric inhibitory polypeptide release.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00280527

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