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  • 1
    Electronic Resource
    Electronic Resource
    The peroxidase isozymes of the wheat kernel: tissue and substrate specificity and their chromosomal location (1987)
    Springer
    Theoretical and applied genetics 73 (1987), S. 701-706 
    Details
    ISSN: 1432-2242
    Keywords: Triticum aestivum ; Peroxidases ; Tissue and substrate-specificity ; Chromosomal location
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Peroxidase isozymes were studied in the Triticum aestivum L. kernel and in nullisomic-tetrasomic and ditelocentric combinations of ‘Chinese Spring’ wheat. Analyses were carried out on different parts of dry kernels (embryo plus scutellum and endosperm) using polyacrylamide and starch gel electrophoresis, different electrophoretic buffer systems and various staining methods. The peroxidase isozymes showed a low substrate-specificity and a high tissue-specificity. The embryo plus scutellum and the endosperm always presented different peroxidase patterns. Endosperm peroxidases were associated with chromosome arms 7DS, 4BL and 7AS; whereas the embryo plus scutellum isozymes were related to chromosome arms 3AL, 3BL and 3DS. The different results obtained using various electrophoretic techniques are due to the buffer system used. All staining procedures employed revealed the same peroxidase isozymes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00260779
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cerebrospinal fluid levels of transition metals in patients with Parkinson's disease (1998)
    Springer
    Journal of neural transmission 105 (1998), S. 497-505 
    Details
    ISSN: 1435-1463
    Keywords: Keywords: Parkinson's disease ; transition metals ; iron ; copper ; manganese ; zinc ; cerebrospinal fluid levels ; serum levels.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary. We compared CSF and serum levels of iron, copper, manganese, and zinc, measured by atomic absorption spectrophotometry, in 37 patients with Parkinson's disease (PD) and 37 matched controls. The CSF levels of zinc were significantly decreased in PD patients as compared with controls (p 〈 0.05). The serum levels of zinc, and the CSF and serum levels of iron, copper, and manganese, did not differ significantly between PD-patient and control groups. There was no influence of antiparkinsonian therapy on CSF levels of none of these transition metals. These values were not correlated with age, age at onset, duration of the disease, scores of the Unified Parkinson Disease Rating Scale of the Hoehn and Yahr staging in the PD group, with the exception of CSF copper levels with the duration of the disease (r = 0.38, p 〈 0.05). These results suggest that low CSF zinc concentrations might be related with the risk for PD, although they could be related with oxidative stress processes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007020050073
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Cerebrospinal fluid levels of transition metals in patients with Alzheimer's disease (1998)
    Springer
    Journal of neural transmission 105 (1998), S. 479-488 
    Details
    ISSN: 1435-1463
    Keywords: Keywords: Alzheimer's disease ; transition metals ; iron ; copper ; manganese ; zinc ; cerebrospinal fluid levels ; serum levels.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary. We compared CSF and serum levels of iron, copper, manganese, and zinc, measured by atomic absorption spectrophotometry, in 26 patients patients with Alzheimer's disease (AD) without major clinical signs of undernutrition, and 28 matched controls. CSF zinc levels were significantly decreased in AD patients as compared with controls (p 〈 0.05). The serum levels of zinc, and the CSF and serum levels of iron, copper, and manganese, did not differ significantly between AD-patient and control groups. These values were not correlated with age, age at onset, duration of the disease, and scores of the MiniMental State Examination in the AD group. Weight and body mass index were significantly lower in AD patients than in controls. Because serum zinc levels were normal, the possibility that low CSF zinc levels were due to a deficiency of dietary intake seems unlikely. However, it is possible that they might be related to the interaction of beta-amyloid and/or amyloid precursor protein with zinc, that could result in a depletion of zinc levels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007020050071
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    Paper (German National Licenses)
    Fulltext
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