ISSN:
1432-1424
Keywords:
gramicidin channel
;
temperature dependence
;
single channel current histograms
;
peptide libration mechanism
;
nonlinear Arrhenius plots
;
metastable states
;
dynamic channel
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Chemistry and Pharmacology
Notes:
Summary A study of the temperature dependence of gramicidin A conductance of K+ in diphytanoyllecithin/n-decane membranes shows the plot of In (single channel conductance) as a function of reciprocal temperature to be nonlinear for the most probable set of conductance, states. These results are considered in terms of a series of barriers, of the dynamics of channel conformation,vis-a-vis the peptide libration mechanism, and of the effect of lipid viscosity on side chain motions again as affecting the energetics of peptide libration.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01868714
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