ISSN:
1420-9071
Keywords:
Carotenoid
;
marine sponge
;
Halichondria okadai
;
sponge associated bacteria
;
Pseudomonas sp.
;
okadaxanthin
;
singlet oxygen quencher
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract To study the origins of biologically active substances in marine sponges, a carotenoid produced by a marine bacterium,Pseudomonas sp. strain number KK10206C, which was associated with a marine sponge,Halichondra okadai, was investigated. A visible absorption spectrum-guided isolation procedure led to the isolation of a novel C50-carotenoid, okadaxanthin. Its structure, 2,2′-bis(4-hydroxy-2-methyl-2-butenyl)-ε,ε-carotene, was elucidated mainly by spectroscopic methods. Okadaxanthin turned out to be a potent singlet oxygen quencher, approximately 10 times as strong as α-tocopherol.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01952874
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