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  • 1985-1989  (3)
  • 99mTc-Sn-N-pyridoxyl-5-methyltryptophan  (2)
  • organic solvents  (1)
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Erscheinungszeitraum
  • 1985-1989  (3)
Jahr
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  • 1
    Digitale Medien
    Digitale Medien
    Intramolecular and liquid structure of 2,2,2-trifluoroethanol by X-ray diffraction (1989)
    Springer
    Journal of solution chemistry 18 (1989), S. 771-784 
    Details
    ISSN: 1572-8927
    Schlagwort(e): Liquid structure ; x-ray diffraction ; 2,2,2-trifluoroethanol ; organic solvents
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Chemie und Pharmazie
    Notizen: Abstract Intramolecular and liquid structure of 2,2,2-trifluoroethanol (TFE) have been investigated by x-ray diffraction at 25°C. The structural parameters for the skeleton of the molecules in the liquid phase are similar to those in the gas phase. The conformers of TFE molecules in the liquid phase are discussed. The O...O distance at about 284 pm and additional F...O one at about 302 pm were found to be characteristic for the first neighbor interactions. Various models (dimers and trimers) have been examined for analyzing the first neighbor structure. The liquid structure was explained in terms of small clusters consisting of two to three molecules rather than of a more extended polymeric network.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00651809
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Comparison of delayed hepatobiliary imaging using 99mTc-Sn-N-pyridoxyl-5-methyltryptophan and 67Ga-citrate imaging for diagnosis of hepatocellular carcinoma (1988)
    Springer
    European journal of nuclear medicine 14 (1988), S. 414-418 
    Details
    ISSN: 1619-7089
    Schlagwort(e): Hepatoma ; 99mTc-Sn-N-pyridoxyl-5-methyltryptophan ; 67Ga-citrate
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Images were obtained both with a biliary agent, 99mTc-Sn-N-pyridoxyl-5-methyltryptophan (99mTc-PMT), and with 67Ga-citrate in 40 cases of hepatocellular carcinoma and in 43 cases of other hepatic diseases and results were compared. Positive results were obtained by delayed 99mTc-PMT imaging in 25 (63%) of 40 cases of hepatoma: the hepatic tumor showed increased uptake in 18 cases (45%) and equilibrated uptake in 7 cases (18%). Positive 67Ga-citrate imaging was found in 28 (70%) of the 40 cases of hepatoma: increased uptake was seen in 24 cases (60%) and equilibrated uptake in 4 cases (10%). Of 15 cases of hepatoma giving negative results in the 99mTc-PMT study, 7 cases (47%) took up 67Ga-citrate, and 6 of these showed increased 67Ga-citrate uptake by the hepatic tumors. A certain relation existed between the degree of histological differentiation of hepatomas and the intensity of 99mTc-PMT uptake by those tumors, while such a histological correlation was denied for 67Ga-citrate uptake by the tumors. Delayed 99mTc-PMT imaging is preferable to 67Ga-citrate imaging for increasing the specificity of diagnosis of hepatoma. 67Ga-citrate should be used in those cases that do not give positive results with 99mTc-PMT.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00254396
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  • 3
    Digitale Medien
    Digitale Medien
    Concentration of 99mTc-Sn-N-pyridoxyl-5-methyltryptophan, a biliary agent, in distant metastases of hepatomas (1985)
    Springer
    European journal of nuclear medicine 10 (1985), S. 255-258 
    Details
    ISSN: 1619-7089
    Schlagwort(e): 99mTc-Sn-N-pyridoxyl-5-methyltryptophan ; Hepatobiliary agent ; Metastasis of hepatoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract During the last 2 years, eight patients with hepatocellular carcinoma who were suspected of having distant metastases have been studied to determine whether a new biliary agent, 99mTc-Sn-N-pyridoxyl-5-methyltryptophan (99mTc-PMT), is taken up by extrahepatic tumors. In all eight patients, scintigrams showed a clearly increased uptake of 99mTc-PMT radioactivity by the extrahepatic tumors. In contrast, an increased uptake by the tumors of gallium citrate Ga 67 was only detected in four of the seven patients examined. The results obtained in this study suggest that 99mTc-PMT is useful both for characterizing the nature of extrahepatic tumors in patients with hepatoma and for detecting the metastases.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00254470
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