ISSN:
0947-6539
Keywords:
asymmetric catalysis
;
hydrogenations
;
palladium
;
phosphorus ligands
;
rhodium
;
Chemistry
;
General Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Optically active phosphorus ligands are widely used in homogeneous asymmetric catalysis. However, among the numerous available structures of this type, the subclass of optically active bisphosphines with at least one chiral phosphorus atom is rather underdeveloped. A bisphosphine with two chiral, nonracemizable bridgehead phosphorus centers, (meso,d/l)-2,2′,3,3′-tetraphenyl-4,4′,5,5′-tetramethyl-6,6′-bis-1-phosphanorborna-2,5-dienyl (BIPNOR), can be obtained by thermolysis of 1,1′-bisphospholyl with diphenylacetylene. Here, we report the resolution of the d/l isomer by means of a chiral palladium complex to give the two optically active forms of BIPNOR. We then investigate the catalytic properties of BIPNOR, incorporated in RhI and RuII catalysts for the hydrogenation of olefins and ketones and in a PdII catalyst for asymmetric alkylation reactions. BIPNOR is shown to give good results in these catalytic reactions.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chem.19970030824
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