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Digitale Medien

Methods for rapidly altering the permeability of mammalian cells (1977)

Heppel, Leon A. ; Makan, Nizar

New York, N.Y. : Wiley-Blackwell

Journal of Supramolecular Structure 6 (1977), S. 399-409

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Details

ISSN: 0091-7419

Schlagwort(e): permeability ; detergents ; ATP ; Life Sciences ; Molecular Cell Biology

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Biologie , Chemie und Pharmazie , Medizin

Notizen: Various agents alter mammalian cells so that they rapidly become nonspecifically permeable to substances that ordinarily do not penetrate intact cells. Thus, toluene renders liver cells permeable to nucleotides and macromolecules. Tween 80 and Tween 60 act in similar fashion, and the effect is reversible. Dextran sulfate reversibly alters the permeability of Ehrlich ascites tumor cells, which offers a tool for studying the control of macromolecular syntheses and other processes. Brief exposure to external ATP alters the permeability of certain transformed mouse cells but not of untransformed cells. The effect of ATP is rapidly reversible.

Zusätzliches Material: 4 Tab.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/jss.400060313

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