ISSN:
1573-8221
Schlagwort(e):
proline-containing oligopeptides
;
Semax
;
gastric ulcer
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Abstract The ACTH4-7 analogue Semax administered intraperitoneally in a dose of 50 μg/kg 1 h before exposure to ulcerogenic factors (ethanol, water immersion immobilization stress) protected gastric mucosa from damage. Postoperative treatment with Semax for 5 days after application of glacial acetic acid on the mucosa prevented acetic acid-induced ulcers and promoted their healing. The antiulcer effects of Semax in the studied dose were comparable with those of tripeptide Pro-Gly-Pro in a dose of 1 mg/kg.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1023/A:1015366229006
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