Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Cyclosporin A  (2)
  • self‐assembled monolayers  (2)
  • 1
    ISSN: 1432-0584
    Keywords: Key words Immunosuppressants ; Cyclosporin A ; FK506 ; KM2210 ; Hematopoiesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Immunosuppressants cyclosporin A (CsA), FK506, and KM2210 modulated colony formations of murine hematopoietic progenitor cells. In a 4-h treatment with CsA, 10 μg/ml increased the formation of colony-forming units of mixed lineages (CFU-Mix) but decreased the formation of highly proliferative potential colony-forming units (CFU-HPP); 1 μg/ml of CsA increased the formations of CFU-HPP, CFU-Mix, and colony-forming units of granulocytes/macrophages (CFU-GM); 0.1 μg of CsA increased the formation of CFU-Mix and burst-forming units of erythroid lineage (BFU-E). Lower doses of CsA appeared to induce an increase in various colony formations. FK506 increased CFU-HPP and CFU-Mix formations at lower doses. Another immunosuppressant, KM2210, increased CFU-HPP and CFU-GM formations but decreased CFU-Mix and BFU-E formations. In a 24-h treatment, 10 μg/ml and 1 μg/ml of CsA inhibited all the colony formations, but 0.1 μg/ml of CsA increased CFU-Mix, CFU-GM, and BFU-E formations. Similarly, 100 ng/ml and 10 ng/ml of FK506 decreased all the colony formations but 1 ng/ml of FK506 increased CFU-HPP and CFU-GM formations. KM2210 inhibited all the colony formations. These findings showed that lower doses of CsA and FK506 appeared to increase the colony formations, although higher doses of these drugs decreased the colony formations, similar to the findings in a 4-h treatment. On the other hand, KM2210 showed opposing effects on colony formation with 4-h and 24-h treatments.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    ISSN: 1432-0584
    Keywords: Immunosuppressants ; Cyclosporin A ; FK506 ; KM2210 ; Hematopoiesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Immunosuppressants cyclosporin A (CsA), FK506, and KM2210 modulated colony formations of murine hematopoietic progenitor cells. In a 4-h treatment with CsA, 10 μg/ml increased the formation of colony-forming units of mixed lineages (CFU-Mix) but decreased the formation of highly proliferative potential colony-forming units (CFU-HPP); 1 μg/ml of CsA increased the formations of CFU-HPP, CFU-Mix, and colony-forming units of granulocytes/macrophages (CFU-GM); 0.1 μg of CsA increased the formation of CFU-Mix and burst-forming units of erythroid lineage (BFU-E). Lower doses of CsA appeared to induce an increase in various colony formations. FK506 increased CFU-HPP and CFU-Mix formations at lower doses. Another immunosuppressant, KM2210, increased CFU-HPP and CFU-GM formations but decreased CFU-Mix and BFU-E formations. In a 24-h treatment, 10 μg/ml and 1 μg/ml of CsA inhibited all the colony formations, but 0.1 μg/ml of CsA increased CFU-Mix, CFU-GM, and BFU-E formations. Similarly, 100 ng/ml and 10 ng/ml of FK506 decreased all the colony formations but 1 ng/ml of FK506 increased CFU-HPP and CFU-GM formations. KM2210 inhibited all the colony formations. These findings showed that lower doses of CsA and FK506 appeared to increase the colony formations, although higher doses of these drugs decreased the colony formations, similar to the findings in a 4-h treatment. On the other hand, KM2210 showed opposing effects on colony formation with 4-h and 24-h treatments.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1573-2711
    Keywords: friction ; self‐assembled monolayers ; hysteresis ; alkanethiols ; alkylsilanes ; nanoindentation ; IFM ; aging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Using interfacial force microscopy (IFM), we investigated the tribological behavior of hexadecanethiol monolayers on Au and films of octadecyltrichlorosilane (ODTS), perfluorodecyltrichlorosilane (PFTS) and dodecane on Si. We observe a strong correlation between hysteresis in a compression cycle (measured via nanoindentation) and friction. Additionally, we suggest that the amount of hysteresis and friction in each film is related to its detailed molecular structure, especially the degree of molecular packing.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Tribology letters 7 (1999), S. 87-90 
    ISSN: 1573-2711
    Keywords: self‐assembled monolayers ; SAM ; silicon ; surface ; MEMS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Microelectromechanical systems (MEMS) are poised to bring the next technology revolution. At present, many of these are fabricated from silicon using lithographic techniques developed in the microelectronics industry. Due to the large surface area to volume ratio on the micrometer scale, surface forces, such as adhesion and friction, are often detrimental to the fabrication and operation of MEMS devices. Thus, one of the key issues in MEMS is surface engineering to reduce adhesion and friction. Here, we present a general strategy for the efficient assembly of organic layers directly onto the silicon surface in both vacuum environment and solution phases via the robust Si–N or Si–O linkage. This is achieved by the reaction between an amine or alcohol functional group and a chlorinated Si surface. The resulting surface assemblies are thermally stable. Characterization by interfacial force microscope (IFM) reveals that these assemblies have very low surface energy and are mechanically stable.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...