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  • 1
    ISSN: 1432-1424
    Keywords: calcium current ; skeletal muscle ; sulfhydryl ; invertebrate muscle
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Summary Voltage-clamp experiments using the three-microelectrode voltage clamp technique were performed on ventroabdominal flexor muscles of the crustacean Atya lanipes. Potassium and chloride currents were found to underlie the normal, passive response of the muscle. Blocking potassium currents with tetraethylammonium and replacing chloride ions with methanesulfonate did not unmask an inward current. By treating the muscle with the sulfhydryl-alkylating agent 4-cyclopentene-1,3-dione an inward current was detected. The current induced by the agent is carried by Ca2+, since it is abolished in Ca2+-free solutions. The induced Ca+current is detected at about -40 mV and reaches a mean maximum value of -78 μA/cm2 at ca. -10 mV. At this potential the time to peak is close to 15 msec.The induced Ca2+ current inactivated with 1-sec prepulses which did not elicit detectable Ca2+ current; the fitted h xcurve had a midpoint of-38 mV and a steepness of 5.0 mV. Measurements of isometric tension were performed in small bundles of fibers, and the effects of the sulfhydryl-alkylating agents 4-cyclopentene-1,3-dione andN-ethylmaleimide were investigated. Tetanic tension was enhanced in a strictly Ca2+-dependent manner by 4-cyclopentene1,3-dione. The amplitude of K+ contractures increased after treatment with N-ethylmaleimide. It is concluded that Ca2+ channels are made functional by the sulfhydryl-specific reagents and that the increase in tension is probably mediated by an increase in Ca2+ influxthrough the chemically induced Ca2+ channels.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    The international journal of advanced manufacturing technology 16 (2000), S. 85-91 
    ISSN: 1433-3015
    Keywords: Key words: Machining; Nickel; Titanium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The paper examines the results of machining tests carried out on two alloys commonly used in the aircraft industry, specifically, alphabeta type titanium alloy Ti6A14V and nickel-based superalloy of type 718. In view of their excellent mechanical properties and their resistance to a wide range of temperatures, these alloys are widely used in the manufacture of turbo-engine parts. They are extremely difficult to machine, however, for various reasons. The present aim is to consider how their drilling, turning, and milling could be made more productive.
    Type of Medium: Electronic Resource
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