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  • 1
    Electronic Resource
    Electronic Resource
    Nocturnal penile tumescence and penile responses in the waking state in diabetic and nondiabetic sexual dysfunctionals (1985)
    Springer
    Archives of sexual behavior 14 (1985), S. 109-129 
    Details
    ISSN: 1573-2800
    Keywords: nocturnal penile tumescence ; sexual arousal ; sexual dysfunction ; impotence ; erectile dysfunction ; sleep ; diabetes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Psychology
    Notes: Abstract This study compared diabetics with sexual dysfunction, nondiabetics with sexual dysfunction, and a group of controls on nocturnal penile tumescence (NPT) during three nights in a sleep laboratory, and penile response to erotic stimulation in the waking state on one of the nights. Both diabetic and nondiabetic dysfunctionals showed less erectile response to erotic films and tape than controls but did not differ from each other. In contrast, the diabetic dysfunctionals showed significantly weaker NPT response than both the nondiabetic dysfunctionals and the controls, and 58% of them (contrasted with 23% of nondiabetic dysfunctionals and 0% of controls) would be classified as organic using minimal NPT (less than 11.5 mm maximal increase in penile circumference during any nocturnal erection) as the sole criterion. There was a significant relationship between NPT and waking erections in response to erotic stimuli, especially in the diabetic dysfunctionals and the controls.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01541657
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Mutational and functional analysis of thekorA andkorB gene products ofStreptomyces plasmid p1J101 (1990)
    Springer
    Molecular genetics and genomics 222 (1990), S. 337-344 
    Details
    ISSN: 1617-4623
    Keywords: Plasmid transfer ; Repressor ; Transcription control ; lac genes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary ThekorA andkorB loci ofStreptomyces lividans plasmid pIJ101 have previously been shown to control expression of the pIJ101tra (formerlykilA) andkilB genes at the transcriptional level. We show here that mutations in translational open reading frames (ORFs) that map within the kor loci abolish repression of theS. lividans lac gene directed by thetra andkilB promoters. Introduction of thekorA andkorB ORFs intoEscherichia coli maxicells under control of anE. coli promoter gave rise to 31 kDa and 10 kDa proteins that correspond in size to the products expected from the sequences of the respective ORFs; these proteins controlled transcription from the pIJ101tra andkilB promoters in theE. coli host. Mutations that affected the KorA or KorB phenotype altered the structure of, or eliminated, the protein products of thekorA andkorB ORFs, further demonstrating that these ORFs encode the functional repressors of the pIJl01kil/kor gene system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00633838
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    Paper (German National Licenses)
    Fulltext
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