ISSN:
1573-2630
Keywords:
glaucoma
;
filtering surgery
;
tissue plasminogen activator
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Since 1987 we have performed, with good results, glaucoma filtering surgery in which the limbo-scleral fistula was closed by an autogenic full blood clot (sclerectomy under a clot). In 8 patients with advanced stages of glaucoma simplex, 1–3 days after sclerectomy under a clot with rise IOP, 25μg of tissue plasminogen activator (tPA) was injected subconjunctivally. Two weeks after surgery normalization of IOP below 15 mmHg and normal outflow facility in all tPA treated eyes were obtained. No increase in early postoperative complications, such as hemorrhage or corneal haze, was attributable to tPA use. In early period after sclerectomy under a clot, when blockage of outflow appears, the use of tPA can cause the re-creation of filtering tract.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00917997
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