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  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Experimental brain research 54 (1984), S. 191-194 
    ISSN: 1432-1106
    Schlagwort(e): Baclofen ; Polysynaptic reflexes ; Spasticity ; Intrathecal injection ; Rabbit
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Intrathecal baclofen is effective in reducing polysynaptic spinal reflexes in awake rabbits. A single lumbar infusion of 2.5–5.0 ng drug caused a significant reduction in the crossed extensor response to electrical stimulation of the plantar surface of the hindlimb. This inhibition lasted 5 h or more. At doses of 3 μ or less, the forelimbs were unaffected.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 33 (1987), S. 99-108 
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Human blood (blood bank, expired) sheared through stainless steel capillary tubing (508 μm ID) is analyzed for plasma hemoglobin to study the effect of shear-induced blood damage within the low-stress regime (stress ≤ 20 Pa). Blood damage results are described in terms of capillary length (related to blood residence time) and wall shear rate for assessing bulk and surface effects. A phenomenological model is proposed to explain these experimental results, obtained over a shear rate range to 7,000 s-1.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 30 (1984), S. 569-577 
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Human blood is sheared in cone-and-plate and parallel-plate rotational viscometers, the latter with variable plate spacings h. Plasma is analyzed for hemoglobin and LDH content before and after shearing to determine the extent of shear-induced blood damage within the low-stress regime (stress ≤ 13 Pa). Geometrical variations in the test apparatus can be accommodated by correlating blood damage with the radially-averaged shear rate. Data on expired blood are shown to imply that much of the damage arises in the bulk fluid, with a smaller contribution from surface effects. Models are proposed to explain these results, obtained over a shear rate range to 5,000 s-1; parallel-plate platen separation is 0.25 〈 h 〈 1.00 mm, cone-and-plate angle is 0.5°, and both systems have platens 100 mm in diameter.
    Zusätzliches Material: 5 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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