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  • 1
    Digitale Medien
    Digitale Medien
    Morphological investigations on cerebellar “neuroblastoma” group (1982)
    Springer
    Acta neuropathologica 56 (1982), S. 22-28 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Cerebellar neuroblastoma ; Desmoplastic medulloblastoma ; Synaptic device ; Granule cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Classic medulloblastoma is a relatively common and distinct clinicopathologic entity consisting of primitive multipotential cells with differentiating capacity to neuroblastic and/or glial cell lines. Desmoplastic medulloblastoma has some features in common with cerebellar neuroblastoma, in which ultrastructural evidence of significant neuroblastic differentiation is extremely rare. We studied three cerebellar tumors with evidence of neuronal differentiation as compared to four classical desmoplastic medulloblastomas. Two of three tumors contained the regions of different degrees resembling desmoplastic medulloblastoma and one consisted of neuroblastic cells exclusively. This spectrum of differentiation suggests a relationship between cerebellar neuroblastoma and medulloblastoma, especially of the desmoplastic type. The nature of cerebellar neuroblastoma and its nosology are briefly discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00691178
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  • 2
    Digitale Medien
    Digitale Medien
    Cerebellar neuroblastoma (1980)
    Springer
    Acta neuropathologica 50 (1980), S. 139-142 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Cerebellar neuroblastoma ; Medulloblastoma ; Synaptic vesicle ; Synapse ; Granule cell
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A cerebellar tumor of a 4-month-old girl was examined by light and electron microscopy. The presence of numerous synaptic vesicles in many cell processes and the occasional synaptic devices warranted the diagnosis of neuroblastoma of the cerebellum. The nature of the tumor is discussed briefly.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00692864
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  • 3
    Digitale Medien
    Digitale Medien
    Folliculo-stellate cell adenoma of the pituitary (1984)
    Springer
    Acta neuropathologica 62 (1984), S. 340-344 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Pituitary gland ; Tumor ; Folliculo-stellate ; Cell adenoma
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary An unusual tumor of the pituitary gland is reported. The most characteristic finding of the present tumor was the presence of numerous “colloid” and mucoid secretions. The cells were stellate in shape and there were intra- or intercellular lumina which were lined by many microvilli and occasional cilia. There were also large accumulations of 10 nm filaments in their cytoplasm. Junctional devices were well formed at the points of mutual contact of these cells. They thus correspond to fetal follicular cells of the anterior pituitary lobe. For this reason, “folliculo-stellate cell adenoma of the pituitary” would best characterize this hitherto undescribed neoplasm.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00687617
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  • 4
    Digitale Medien
    Digitale Medien
    Ultrastructural observation on a colloid cyst of the third ventricle (1984)
    Springer
    Acta neuropathologica 65 (1984), S. 41-45 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Colloid cyst ; Third ventricle ; Ultrastructure ; Pathogenesis ; Rathke's cyst
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The case involves a colloid cyst of the third ventricle in a 20-year-old man. The lining epithelia of the cyst were composed of two different types of epithelial cells; stratified squamous cells and mucincontaining columnar cells. The presence of both squamous and glandular cells in the cyst wall supports the contention that the colloid cyst in the present case derived from an non-neuroepithelial source. The clinico-pathology of this cystic tumor is compared here with other epithelial cysts of the central nervous system (CNS), especially Rathke's cyst.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00689826
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  • 5
    Digitale Medien
    Digitale Medien
    Atypical senile dementia with widespread Lewy type inclusion in the cerebral cortex (1980)
    Springer
    Acta neuropathologica 49 (1980), S. 187-191 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Atypical senile dementia ; Lewy body ; Cortical ; Lewy-like body
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary An atypical case of senile dementia is reported which shows senile plaques, neurofibrillary tangles, granulovacuolar degeneration, and Hirano bodies and numerous Lewy bodies in the pigmented neurons of the brain stem, and Lewy-body-like inclusions in the cerebral cortex. The inclusions in the cerebral cortex had a strong resemblance to the Lewy bodies in the substantia nigra, though a few histochemical and ultrastructural differences were observed. The pathological findings were unexpected since the parkinsonian syndrome was not recognized.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00707105
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  • 6
    Digitale Medien
    Digitale Medien
    Infantile neuroaxonal dystrophy (1978)
    Springer
    Acta neuropathologica 41 (1978), S. 257-259 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Infantile neuroaxonal dystrophy ; Sural nerve biopsy ; Electron microscope ; Schwann cell inclusions
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Abnormal Schwann cell inclusion is reported in biopsied peripheral nerve in a cases of infantile neuroaxonal dystrophy. In addition to non-specific dystrophic changes of the axons, the Schwann cells contained several distinct bodies which were composed of stacks of irregularly disposed membranes; in some instances, transformed Schwann cell cytoplasm was distinded with similar bodies. This change has not been reported on this condition and its significance is briefly discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00690446
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  • 7
    Digitale Medien
    Digitale Medien
    Primary rhabdomyosarcoma of the cerebrum (1979)
    Springer
    Acta neuropathologica 45 (1979), S. 111-115 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Brain tumor ; Rhabdomyosarcoma ; Mesenchymal cell ; Myotube ; Ultrastructure
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A case of primary cerebral rhabdomyosarcoma in a 51-year-old female is reported. The histogenesis of this tumor is discussed. The clinicopathological features of 10 previously reported similar tumors of the CNS are briefly reviewed. Histologically the tumor was polymorphic, but composed of poorly differentiated cells interpreted as rhabdomyoblasts without definite cross-striation. Electron microscopy established that the poorly differentiated cells were of rhabdomyosarcomatous nature, compatible with presumptive myoblasts and analogous to developing fetal muscle.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00691888
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  • 8
    Digitale Medien
    Digitale Medien
    Crystalloid inclusions reminiscent of Hirano bodies in autolyzed peripheral nerve of normal Wistar rats (1979)
    Springer
    Acta neuropathologica 47 (1979), S. 231-236 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Hirano bodies ; Peripheral nerve ; Autolysis ; Wistar rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary In a study of experimental autolysis of peripheral nerves of normal Wistar rats, crystalloid inclusions similar to Hirano bodies were observed. They occurred in the nuclei and cytoplasms of Schwann cells and in myelinated axons. They first developed after a 12-h autolysis and increased in number and size with time. Their fine structure, localization, and morphogenesis are discussed in relation to the autolysis of the cellular organelles.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00690551
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  • 9
    Digitale Medien
    Digitale Medien
    Pleomorphic intra-neuronal polyglucosan bodies mainly restricted to the pallidium (1983)
    Springer
    Acta neuropathologica 62 (1983), S. 159-163 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Pleomorphic polyglucosan body ; Bielschowsky body ; Lafora body ; Corpora amylacea
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary A rare case with pleomorphic intra-neuronal polyglucosan bodies is reported. A 45-year-old man died of gastric carcinoma with extensive visceral involvement. The autopsy showed numerous intra-neural pleomorphic PAs-positive deposits reminiscent of Bielschowsky bodies in the lateral segments of the pallidum, substantia nigra, and brain stem on both sides. Their histochemical properties were consistent with polyglucosan. The bodies were ultrastructurally composed of filamentous structures and seen in perikarya, axons, and dendrites. Occasionally, spotty electron-dense material was seen in the center of the bodies. The filaments were selectively stained with thiocarbohydrazide method after Thiéry, indicating their chief component as glucose polymers. The bodies are compared with Bielschowsky bodies, Lafora bodies, corpora amylacea, and related bodies, and their nature and significance are briefly discussed.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00684936
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  • 10
    Digitale Medien
    Digitale Medien
    Hypertrophy of the olivary nucleus (1986)
    Springer
    Acta neuropathologica 69 (1986), S. 132-138 
    Details
    ISSN: 1432-0533
    Schlagwort(e): Olivary hypertrophy ; Neurofilaments ; Paired helical filaments ; Straight tubules ; Progressive supranuclear palsy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The fine structure of the hypertrophic olive is reported in a case of progressive supranuclear palsy, the cause of which would be attributed to extensive symmetrical lesions in the dentate nuclei of the cerebellum and central tegmental tracts of the pons. Ultrastructurally, the enlarged neurons and their processes showed massive aggregations of neurofilaments, large accumulations of concentric laminated bodies, and occasional abnormal neurofibers (paired helical filaments and straight tubules). Their implications are briefly discussed in relation to olivary hypertrophy. Eosinophilic globules were seen in a neuron. Glomeruloid bodies were not seen.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00687049
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