Bibliothek

feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    ISSN: 1432-0428
    Schlagwort(e): Chinese hamster ; spontaneous diabetes ; glucosuria ; ketonuria ; glycogen ; glycogen accumulation ; retina ; Müller cell ; kidney ; distal tubule ; pancreatic islet ; a cell ; Β cell ; D cell ; electron microscopy
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary Intracellular glycogen deposits were consistently found in the retina, kidney and pancreatic islets of diabetic-ketonuric Chinese hamsters. Accumulation of glycogen in the outer nuclear layer of the retina was mostly associated with severity of the disease, but was not related to age or sex. The type of retinal cell involved in the accumulation of glycogen was not clearly established. However, the position of the affected cell, side by side with retinal neurons, suggests that the glycogen deposits were within Müller cells. These giant glias normally synthesize and store glycogen. All ketonuric Chinese hamsters examined showed some accumulation of glycogen in distal tubules of the kidney. This abnormal glycogen was not found in glucosuric non-ketonuric or in nondiabetic Chinese hamsters. Variable amounts of glycogen were found inΒ cells of pancreatic islets of diabetic hamsters, as reported by others. However, accumulation of glycogen was also found inα and D islet cells from 2 middle aged Chinese hamsters with long term glucosuria and recent ketonuria. Abnormal glucose and glycogen metabolism seem to play an important role in the pathogenesis of diabetes in the Chinese hamster.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...