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  • Biochemistry and Biotechnology  (3)
  • Mastomys natalensis  (2)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Cellular and molecular life sciences 41 (1985), S. 472-474 
    ISSN: 1420-9071
    Schlagwort(e): Mouse, Swiss ; Mastomys natalensis ; rat, C. F. strain ; acid hydrolases, liver ; Plasmodium berghei infection
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary Changes in liver acid hydrolase activities during the infection of albino rats,Mastomys or mice withPlasmodium berghei are described. B-Glucosidase, B-galactosidase and N-acetyl-B-D-glucosaminidase exhibited widely different responses with acid phosphatase and cathepsin-B the least responsive and are likely to be causally related to immunity of animals.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    ISSN: 1420-9071
    Schlagwort(e): Acanthocheilonema viteae ; Mastomys natalensis ; γ-glutamyl-transpeptidase ; lymphoid tissues ; filarial infection ; immunosuppression
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Medizin
    Notizen: Summary DuringAcanthocheilonema viteae infection, the specific activity of γ-glutamyltranspeptidase (γ-GT) increased in peritoneal exudate cells and bone marrow and decreased in lymphnodes ofMastomys natalensis throughout the course of infection. However, though there was an increase in specific activity of γ-GT in thymus and spleen during the prepatent phase ofA. viteae infection, the level either returned to normal or decreased during the latent phase of infection. A close correlation was observed between the host's immune status duringA. viteae infection and the level of γ-GT in lymphoid tissues.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 38 (1991), S. 181-190 
    ISSN: 0006-3592
    Schlagwort(e): solventogenic metabolism ; NADH content ; NADH fluorescence ; continuous fermentation ; butanol biosynthesis ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: With a constant glucose feed concentration, the change in the continuous culture dillution rate resulted in an altered fermentation profile and the cellular NADH content. The cultures growing at high dillution rates demonstrated an oxidative metabolism low NADH and butanol concentrations. The low specific NADH flourescence (F/X) at high butanol production rates suggested that a rapid regeneration of NADH to NAD is essential for a high solventogenic culture activity. The culture florescence and butanol concentration remained constant in the solventogenic dilution rate range of D = 0.05-0.2 h-1 with an inverse relationship between the specific flourescence (F/X) and the specific butanol production rate, qB. Flourometric NADH observations were confirmed by enzymatic NADH determination. The stiochiometric “Fermentation Equation” was used to check the experimental data consistency and to investigate the role of the available biosynthetic and reduction energy on the culture metabolic activities under different growth conditions. The butanol concentration in the broth was stabilized in a fed-batch process when the culture NADH fluorescence was being controlled through the addition of fresh medium.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    Digitale Medien
    Digitale Medien
    New York, NY [u.a.] : Wiley-Blackwell
    Biotechnology and Bioengineering 38 (1991), S. 191-195 
    ISSN: 0006-3592
    Schlagwort(e): continuous flow acetone-butanol fermentations ; reduction energy ; solvent production activity ; inlet sugar concentrations ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The continuous flow acetone-butanol fermentation conducted at lowered inlet feed sugar concentrations and at a constant dilution rate D =0.075 h-1 demonstrated a significant decreases in the availability of the cell population “reduction energy” (F/X), resulting in an exclusive accumulation of intermediate acids under those conditions. The cultures resumed its solvent production activity when the inlet sugar concentration in the feed stream was increased from 20 to 40 g/L at the same low growth/dilution rates. A linear correlation between the culture reduction content (F/X) and the specific butanol rate (qB) was observed under the present conditions, indicating the necessity of the NADH availability for the increased solvent production.
    Zusätzliches Material: 6 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 5
    Digitale Medien
    Digitale Medien
    Chichester : Wiley-Blackwell
    Journal of Chemical Technology AND Biotechnology 73 (1998), S. 23-30 
    ISSN: 0268-2575
    Schlagwort(e): vitamin C ; structured mathematical model ; continuous culture kinetics ; sorbose ; sorbitol ; Chemistry ; Biochemistry and Biotechnology
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The kinetics of the biotransformation of D-sorbitol to L-sorbose by Acetobacter suboxydans (NRRL B-72) features both substrate and product inhibition. Model-based reactor operating strategies can eliminate the inhibitions and improve the yield and productivity of the fermentation. Unstructured models are usually unable to acknowledge complex intracellular physiological changes and therefore their application to dynamic growth conditions is limited. By considering RNA as a bottleneck growth limiting compound a structured mathematical model was developed to describe the transient growth of Acetobacter suboxydans. The model parameters were determined by a non-linear regression technique which minimized the deviation between the model prediction and the experimental (extracellular and intracellular) continuous culture data. The model was used to simulate the transient culture behaviour during the step-down in the dilution rates (from 0·1 h-1 to 0·05 h-1) in the continuous culture experiments. The experimental results and the model simulation results showed reasonable agreement. © 1998 Society of Chemical Industry
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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