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Digitale Medien

Extracellular glycosaminoglycans (GAG) released by chick embryonic fibroblasts (1984)

Evangelisti, R. ; Bodo, M. ; Caruso, A. ; [weitere]

Springer

Cell & tissue research 238 (1984), S. 241-245

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Details

ISSN: 1432-0878

Schlagwort(e): Glycosaminoglycans ; Fibroblasts ; Receptors ; Secretory cells ; Lectin

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie , Medizin

Notizen: Summary Administration of Concanavalin A (Con A) to cultured skin fibroblasts derived from chick embryos at two developmental stages produce variations in the relative concentration of individual glycosaminoglycan (GAG) secreted by the cells. This effect is different: at 7 days (increase of hyaluronic acid and dermatan sulphate and decrease of chondroitin sulphate) and at 14 days (dermatan sulphate is not detectable). All the cells bind the Con A specifically, but a different pattern of agglutination is present in fibroblasts of the two embryonic ages. Since Con A is well known to bind carbohydrate-containing surface proteins, the result suggests that the release of GAG by chick embryonic fibroblasts can be modulated by cell surface receptors.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00217295

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