ISSN:
1612-1112
Schlagwort(e):
Capillary GC-MS
;
Methylmalonic acid
;
Metabolic diseases
;
GC-MS
;
Stable isotopes
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Chemie und Pharmazie
Notizen:
Summary Because methylmalonic acid (MMA) accumulates in the body fluids of patients suffering from inherited metabolic disorders involving its pathway, the quantitation of this metabolite is not only fundamental to diagnosis but is also important in the follow-up of affected patients under treatment. We describe the method set up and used in our laboratory for the measurement of MMA in body fluids and propose its application to plasma as the reference method for the biochemical diagnosis and follow-up of methylmalonic acidaemias.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF02263866
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