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HBV, HDV and HIV infections in 242 drug addicts: Two-year follow-up (1988)

Mandelli, C. ; Cesana, M. ; Ferroni, P. ; [weitere]

Springer

European journal of epidemiology 4 (1988), S. 318-321

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Details

ISSN: 1573-7284

Schlagwort(e): Hepatitis B ; Hepatitis delta ; Human immunodeficiency virus ; Drug addicts

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract Of 242 north Italian heroin addicts, 24 (9.9%) were HBsAg positive. HBeAg was positive in two of them (8.3%), anti-HBe in 16 (66.6%) and anti-HDV in 21 (87.5%). Of the 218 HBsAg negative, 182 (83.5%) had anti-HBc, 72 (33.0%) anti-HBe and 97 (44.5%) anti-HBs. One-hundred-eighty-five drug addicts were anti-HIV positive (76.4%); 77 of these (41.6%) were asymptomatic, 93 (50.3%) had PGL and 15 (8.1%) ARC. T4+ cell count was significantly lower in subjects with ARC as was T4+/T8+ ratio in subjects with PGL and ARC. During a median follow-up of 9.5 months (range 4–25), we observed three new cases of hepatitis (two caused by NANBV and one by HBV with HDV coinfection) and one new HIV infection. Ten anti-HIV positive subjects developed PGL and one AIDS.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00148917

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