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  • hybrid systems  (2)
  • Acetylcholine release  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 327 (1984), S. 180-182 
    ISSN: 1432-1912
    Schlagwort(e): SCH 23390 ; Dopamine receptors ; Corpus striatum ; Adenosine cyclic monophosphate ; Acetylcholine release
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The agonistic and antagonistic effects of the new compound SCH 23390 were tested in functional model systems for the D-1 dopamine receptor and for the D-2 dopamine receptor in vitro. In superfused rat neostriatal slices the increase in the efflux of cyclic AMP was used as a parameter for D-1 receptor stimulation. D-2 receptor stimulation was measured as the decrease in the K+-evoked release of [3H]-acetylcholine. SCH 23390 had no agonistic activity in these two models. SCH 23390 was a potent antagonist of the stimulating effect of dopamine in the D-1 receptor model (apparent pA2=7.28). SCH 23390 also antagonized the effect of the D-2 receptor agonist LY 141865 in the D-2 receptor model (apparent pA2=6.34). This D-2 receptor antagonism proved to be of a competitive nature.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Applied intelligence 11 (1999), S. 5-13 
    ISSN: 1573-7497
    Schlagwort(e): neural networks ; knowledge representation ; structured knowledge reasoning ; connectionism ; symbol processing ; hybrid systems
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract This collection of articles is the first of two parts of a special issue on “Neural Networks and Structured Knowledge.” The contributions to the first part shed some light on the issues of knowledge representation and reasoning with neural networks. Their scope ranges from formal models for mapping discrete structures like graphs or logical formulae onto different types of neural networks, to the construction of practical systems for various types of reasoning. In the second part to follow, the emphasis will be on the extraction of knowledge from neural networks, and on applications of neural networks and structured knowledge to practical tasks.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    Digitale Medien
    Digitale Medien
    Springer
    Applied intelligence 12 (2000), S. 7-13 
    ISSN: 1573-7497
    Schlagwort(e): neural networks ; rule extraction ; knowledge representation ; structured knowledge ; connectionism ; hybrid systems
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Informatik
    Notizen: Abstract As the second part of a special issue on “Neural Networks and Structured Knowledge,” the contributions collected here concentrate on the extraction of knowledge, particularly in the form of rules, from neural networks, and on applications relying on the representation and processing of structured knowledge by neural networks. The transformation of the low-level internal representation in a neural network into higher-level knowledge or information that can be interpreted more easily by humans and integrated with symbol-oriented mechanisms is the subject of the first group of papers. The second group of papers uses specific applications as starting point, and describes approaches based on neural networks for the knowledge representation required to solve crucial tasks in the respective application. The companion first part of the special issue [1] contains papers dealing with representation and reasoning issues on the basis of neural networks.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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