ZIB

Treffer pro Seite

Treffer 1 - 1 | 1 Treffer

Sortierung

Digitale Medien

The role of the pedunculopontine region in basal-ganglia mechanisms of akinesia (1999)

Munro-Davies, L. E. ; Winter, J. ; Aziz, T. Z. ; [weitere]

Springer

Experimental brain research 129 (1999), S. 511-517

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1432-1106

Schlagwort(e): Key words Parkinson’s Disease (PD) ; Pedunculopontine nucleus (PPN) ; Akinesia ; Kainic acid (KA)

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Abstract The akinesia of Parkinsonism is relieved by pallidotomy and subthalamic nucleotomy, but not by thalamotomy. Therefore, this disabling symptom probably depends upon connections other than the pallidal-thalamocortical tracts, possibly efferents of the medial pallidum descending to the upper brainstem. We have previously demonstrated akinesia in the normal monkey following radiofrequency lesioning in the region of the pedunculopontine nucleus (PPN), one of the primary targets for descending pallidal outflow. Here, we confirm that selectively destroying neurones in the PPN area, whilst sparing fibres of passage, results in an akinetic state in normal macaques.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/s002210050921

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 1 | 1 Treffer