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  • 11
    Digitale Medien
    Digitale Medien
    Hemophilus influenzae adherence to and absorption from the nasal mucosa of guinea pigs (1989)
    Springer
    European archives of oto-rhino-laryngology and head & neck 246 (1989), S. 218-221 
    Details
    ISSN: 1434-4726
    Schlagwort(e): Mucosal absorption ; Bacterial adherence ; Hemophilus influenzae ; Outer membrane vesicles
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Summary The adherence to and the absorption from nasal mucosal epithelium of type b and non-typeable strains of Hemophilus influenzae were studied in guinea pigs. H. influenzae bacteria were administered to the nose as 4×107 organisms in 1.0 ml saline. The outer membrane vesicles (OMV) of H. influenzae were used in the absorption study. Scanning electron microscopic studies showed that H. influenzae cells attached to both ciliated and non-ciliated cells of the nasal mucosa. Histological studies showed that OMV were absorbed through the nasal mucosa, mainly from ciliated cells. Further, penetration of OMV through the nasal mucosa of immunized animals was reduced when compared with that of non-immunized ones.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00453666
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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