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  • 11
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 152 (1993), S. 331-333 
    ISSN: 1432-1076
    Keywords: Campomelic dysplasia ; Bone dysplasia ; Incidence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Campomelic dysplasia (CD) is a rare skeletal dysplasia. The incidence, reported in the literature, is 0.05–0.09 per 10000 live, births. During the period December 1985–December 1990 there were 18350 live births with 4 cases of CD at Aker University Hospital in Oslo, Norway. This gives an incidence of CD in our observation period of 2.2 per 10000. Eliminating our first case, because of Pakistani decent, the total incidence is 1.6 per 10000 among Norwegian infants which is much higher than the incidence previously mentioned. Perhaps CD is under-reported and a high proportion of patients remain undiagnosed. We present four cases and discuss the incidence.
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 134 (1980), S. 201-204 
    ISSN: 1432-1076
    Keywords: Chromosome 9 ; Autosomal aberrations ; Mental retardation ; Clinical syndromes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A partial deletion of the short arm of chromosome 9 is reported in a female newborn and a 12.5 yearold male. The features expressed by both patients, and especially the peculiar type of the craniofacial dysmorphism, confirm the existence of a typical clinical syndrome associated with this partial autosomal monosomy.
    Type of Medium: Electronic Resource
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  • 13
    Electronic Resource
    Electronic Resource
    Springer
    European journal of clinical pharmacology 25 (1983), S. 739-742 
    ISSN: 1432-1041
    Keywords: terbutaline ; pressurised aerosol ; bronchial asthma ; pear-shaped extender ; IPPV ; bronchodilatation ; drug efficiency
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The efficacy of terbutaline inhaled from different aerosol systems was studied in 13 adult asthmatics. Terbutaline 1 mg was delivered from a pressurised aerosol, 1 and 4 mg were inhaled from a nebuliser, 1 mg was inhaled through a pressurised aerosol with a pear-shaped, 750 ml spacer, and 1 mg was inhaled from a nebuliser with Intermittent Positive Pressure Ventilation (I.P.P.V.). An open, randomized, cross-over design was used. The bronchodilator effect was evaluated by recording hourly flow-volume curves and the FEV1.0 for 5 h after treatment. No significant difference in bronchodilatation was observed after inhalation of 1 mg terbutaline from different aerosol systems, except following use of the nebuliser, which required approximately four times as much terbutaline to obtain the same effect as the ordinary spray.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    Springer
    Il nuovo cimento della Società Italiana di Fisica 16 (1994), S. 1447-1455 
    ISSN: 0392-6737
    Keywords: Disperse systems ; Molecular biophysics ; Physical chemistry of solutions of biological macromolecules ; Conference proceedings
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary The aggregation behaviour of zinc-free insulin has been studied by small-angle neutron scattering as a function of protein concentration,pH, and ionic strength of the solution. The distance distribution functions for the 12 samples have been obtained by indirect Fourier transformation. The weight-averaged molecular mass and thez-averaged radius of gyration were determined. Both quantities vary systematically with the experimental conditions. They increase with decreasingpH and with increasing ionic strength. The radius of gyration scales as a power law of the weight-average mass with the exponent 0.44. A similar scaling is found for a set of oligomers structures based on the crystal structure of zinc-free insulin. The mass distribution between the oligomers was determined by a model based on these oligomers. The results from this model and the Fourier transformations have been compared to an equilibrium model recently introduced by Kadimaet al. The model takes into account the variation of the effective charge of the monomer withpH and ionic strength. The neutron scattering results agree well with the predictions of the model.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 113 (2000), S. 1595-1604 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: We show that transient electron spin resonance (ESR) spectra of short lived radical pairs can be written formally as a superposition of Lorentzian-like lines and the corresponding dispersive lines. The coefficients to these spectral components depend strongly on the frequency and amplitude of the microwave (mw) field and consequently a variety of spectral forms may result. The coefficients, and thus the spectral form, are determined by the interradical interaction induced rate of change of the longitudinal and transversal electron spin polarization. The longitudinal polarization is responsible for the well known chemically induced dynamic electron polarization (CIDEP) which changes the intensity of the lines without affecting the line shape. The transversal polarization is shown to be responsible for the antiphase structure (APS) in accordance with our previous proposition [J. Chem. Phys. 109, 8743 (1998)]. A simple one re-encounter model calculation illustrates and explains qualitatively most of the observed APS characteristics. Numerical calculations are used to discuss anomalously large APS splitting. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 136 (1996), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Dermatophytes such as Trichophyton species are common human pathogens, the infection of which results in dermatophytosis (also known as ringworm). Several laboratory tests are used routinely for the diagnosis of dermatophytosis, but they are either slow or lacking specificity. Through examination of genomic DNA from Trichophyton dermatophytes and other fungi in arbitrarily primed PCR, it was shown that a random primer 5′-ACCCGACCTG-3′ produced bands of 4.3 kb, 1.9 kb, 1.7 kb and 0.7 kb in T. rubrum DNA, bands of 2.5 kb, 1.9 kb and 0.8 kb in T. mentagrophytes var. interdigitale and T. mentagrophytes var. mentagrophytes DNA, and bands of 2.5 kb, 1.9 kb, 1.5 kb and 0.9 kb in T. tonsurans DNA. This primer amplified bands of different sizes in other fungal DNA. Therefore, based on the distinct band patterns observed in arbitrarily primed PCR using this primer, T. rubrum, T. mentagrophytes and T. tonsurans dermatophytes could be rapidly differentiated.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    FEMS microbiology letters 145 (1996), S. 0 
    ISSN: 1574-6968
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: Abstract Candida species are opportunistic human pathogens capable of causing a variety of clinical diseases. Rapid and precise identification of Candida to species level is essential for effective treatment and management strategies. Conventional diagnosis of candidiasis is sometimes slow and variable. By using a random primer 5′-ACGGGCCAGT-3′ in arbitrarily primed polymerase chain reaction, seven common Candida species (i.e. C. albicans, C. guilliermondii, C. parapsilosis, C. krusei, C. lipolytica, C. tropicalis and C. (Torulopsis) glabrata) produced characteristic DNA band patterns, which enabled rapid determination to species level among them. Further analysis of the nucleotide sequences of Candida specific fragments should improve our understanding of the molecular structures and possible functions of the gene regions involved.
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 31 (1966), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 30 (1965), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: To study the effect of pH and divalent cations such as Mg and Ca on rehydration of freeze-dried meat, a model system of freeze-dried myofibrils was designed. The fibrils were dried at pH 5.4, 6.0, and 7.0, with and without addition of Mg and Ca, in the concentrations found in meat. The freeze-dried fibrils were rehydrated after homogenization in the rehydrating solution; and by diffusion of the solution into the dried fibril mass. When the fibrils were homogenized the cations increased the water-holding capacity of the sedimented fibrils. An increase in the water-holding capacity with higher pH was apparent only after the cations were added. When the fibrils were rehydrated through diffusion, the cations decreased the hydration. Increased hydration capacity with higher pH was found with and without the cations.
    Type of Medium: Electronic Resource
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  • 20
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 26 (1961), S. 0 
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Preliminary observations were made on biopsy and post-mortem samples from six Danish Landrace barrows. Additional studies were also conducted on post-mortem muscle samples from 30 Danish Landrace pigs of known breeding and nutrition. The biochemical characteristics studied were related to the continuous post-mortem measurements of pH and temperature, which were used to predict muscle structure. These data imply that the biopsy samples from pigs that ultimately showed the severe depression and elevation in pH pattern, contained greater total glycogen, lower percentage of acid-soluble glycogen, and faster phosphorylase activity. Similarly, these pigs possessed a smaller pyruvic acid pool and a greater lactic acid concentration. Results from measurements of methylene blue reduction, in the presence of lactate, suggest that the methylene blue is reduced much more slowly in muscles from pigs with the type 4 pH pattern. Although this criterion was significantly correlated with zinc concentration, ultimate color intensity, and water-binding capacity, special emphasis was placed on the severe limitations that must be imposed on interpretation of this measurement. The significant correlations collectively suggest, however, that if the samples showed a rapid reduction of methylene blue, they were ultimately uniform in color, dry in appearance, and firm in structure. Significant additional correlations were shown for numerous biochemical characteristics of pork muscle tissue.
    Type of Medium: Electronic Resource
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