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  • 11
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 14 (1967), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 12
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 16 (1969), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— The subcellular distribution of N-acetyl-aspartate, N-acetyl-aspartyl-glutamate, N-acetyl-glutamate and glutathione (reduced) was investigated. Lactate dehydrogenase, potassium, glutamate and aspartate were employed as markers of the cytoplasmatic compartments. Fumarate hydratase and choline acetyltransferase were used as mitochondrial and synaptosomal markers respectively.Our data show that the highest concentrations of NAA, NAGA, NAAGA and glutathione were localized in the supernatant with a smaller peak in the crude mitochondrial (P2) fraction. On subfractionating P2, NAA was distributed similarly to aspartate and K+ with a peak in the synaptosome (B) fraction, while glutathione and NAAGA were localized in the mitochondrial fraction. NAA, aspartate and K+ were more readily released than glutathione and NAAGA from their particulate form on exposure to hypo-osmotic conditions.
    Type of Medium: Electronic Resource
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  • 13
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract— Following intracranial and intraperitoneal injection of acetyl-l-[U-14C]aspartate into mice about 5% and 0.7% of the radioactivity, respectively, was recovered from the brain after 30 min.On chromatographic separation of the cationic and anionic compounds on a Dowex 50 column, the former fraction contained about 60% of the radioactivity, predominantly as labelled aspartate and glutamate. The anionic compounds, containing 20% of the labelled compounds, were fractionated in several chromatographic systems and resolved into a great variety of labelled peptidic compounds of which five acetyl-[U14-C]aspartyl peptides, containing two to four amino acids, were purified. One of these, acetyl-aspartyl glutamine, has not previously been found in brain.
    Type of Medium: Electronic Resource
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  • 14
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 1558-1562 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Carbon films were deposited by rf bias sputtering of a carbon target in argon. Bias voltage and argon pressure were varied systematically. Hardness, internal stress, density, hydrogen content, and infrared absorption were measured as functions of the preparation parameters. From the IR measurements the bond ratio of sp3 to sp2 was calculated and the total amount of hydrogen in the films was determined by elastic recoil detection. The hydrogen content was found to be much lower than for films prepared by plasma decomposition of hydrocarbons. Because the film thickness was in the range of 500 nm, the hardness was measured with an ultralow-load diamond indenter. For these measurements the indentation depth was about 60 nm. The internal stress was determined by the bending beam method. The coordination number, number density, and the filling factor were calculated from the measured values. The results have been compared to those for films deposited by plasma decomposition of hydrocarbons.
    Type of Medium: Electronic Resource
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  • 15
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 66 (1989), S. 5805-5808 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: With an ultralow load indenter the hardness H and the Young's modulus E of amorphous hydrogenated carbon and silicon films, prepared under different conditions, were determined. The values of the hardness of a-C:H, corrected for the elastic recovery, are about 1/3 of the values measured by the Knoop method. The results show that the hardness of a-C:H and a-Si:H are proportional to Young's modulus [(H/E)C =0.115, (H/E)Si =0.093]. In previous works a proportionality of H and E for metal and metal-metalloid glasses, respectively, already has been found.
    Type of Medium: Electronic Resource
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  • 16
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 66 (1989), S. 4729-4735 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In this study diamondlike a-C:H films have been prepared by different methods: In our first experiment a-C:H films were deposited by plasma decomposition of methane at different bias voltages. In the second experiment a-C:H films with high hardness were implanted with 400-keV C+ ions and different doses between 1013 and 1017 ions/cm2 . Subsequently, the following mechanical properties of the films were measured: The shear modulus μ by the frequency of the surface phonon (Rayleigh wave), the stiffness S by an ultralow load indentation of diamond. The Young's modulus and the Poisson's ratio were calculated from μ and S. The internal stress σ was determined with the bending beam method. From the Young's modulus E and the internal stress σ, the average strain ε of the films has been calculated. From the behavior of ε it was concluded that a phase transition from amorphous diamondlike to amorphous graphitelike a-C:H films occurred with increasing substrate bias voltage.
    Type of Medium: Electronic Resource
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  • 17
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 1018-1022 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Diamondlike a-C:H films have been deposited by decomposition of C2H2. By the combination of Brillouin scattering and the ultralow load indentation technique, the following mechanical properties of the films were studied: the microhardness H, the Young's modulus E, the shear modulus μ, and the Poisson's ratio ν. From the measured data of mass density, hydrogen concentration, and the ratio of sp3/sp2 bonds the filling factors of these films were calculated. The results show that the hardness, Young's modulus, and shear modulus of these films depend strongly on the volume concentration of voids and are directly proportional to the filling factor.
    Type of Medium: Electronic Resource
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  • 18
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 67 (1990), S. 6772-6778 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A series of a-Si:H films has been prepared by rf sputtering in a H2-Ar gas mixture. To obtain films with different hydrogen content the hydrogen portion of the gas mixture was changed from 0% to 20%. The shear modulus μ was then measured by the frequency of the surface phonon (Rayleigh wave). The stiffness S and the ultramicrohardness H were measured by using a nanoindenter. From the shear modulus μ and the stiffness S, the Young's modulus E and Poisson's ratio ν were calculated. The intrinsic mechanical stress was measured by the bending-beam method. With increasing hydrogen content of the films, the decrease of Young's modulus, microhardness, and internal stress are observed.
    Type of Medium: Electronic Resource
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  • 19
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 1378-1380 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Gas evolution experiments have been performed on hydrogenated amorphous carbon (a-C:H) films prepared by plasma deposition. Two series of films are studied: in series I, C2H2 is used as a process gas at a fixed bias voltage while the gas pressure is varied, and in series II, CH4 is employed at a fixed gas pressure, and the bias voltage is changed. The results are compared to infrared absorption data and density measurements and support the presence of a void network in the amorphous material, the extent of the void network depending on the deposition conditions.
    Type of Medium: Electronic Resource
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  • 20
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 67 (1990), S. 487-494 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Diamondlike a-C:H films have been deposited by plasma decomposition of C2 H2. 50 samples were prepared with a systematic variation of the deposition parameters: the substrate bias voltage was between −100 and −1400 V and the C2 H2 gas pressure was between 4×10−4 and 2.6×10−1 mbar. The following properties of the films were measured: the density by Rutherford backscattering, the total concentration of hydrogen by elastic recoil detection, the bonding ratio sp3 /sp2 by infrared spectroscopy, the internal stress by the bending beam method, and the hardness with a Knoop microhardness tester. It has been shown that the hardness and other mechanical properties cannot be correlated to the average carbon coordination number mc. This is because mc is calculated under the assumption of a homogenous single-phase model, which does not seem to be justified. It is demonstrated that the mechanical properties can be explained by the application of a void model.
    Type of Medium: Electronic Resource
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