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  • 11
    Electronic Resource
    Electronic Resource
    A study of four cases of extra-orbital giant cell angiofibroma with documentation of some unusual features (2001)
    Oxford UK : Blackwell Science Ltd
    Histopathology 39 (2001), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A study of four cases of extra-orbital giant cell angiofibroma with documentation of some unusual features Aims: To document the clinical, light microscopic, immunohistochemical and ultrastructural features of four cases of extra-orbital giant cell angiofibromas. Methods and results: Sections of formalin-fixed paraffin-embedded specimens were studied by haematoxylin and eosin, reticulin and immunohistochemical stains. Electron microscopy was carried out in two cases on tissue fixed in formalin. The age of the patients ranged from 30 to 41 years. Two patients presented with a soft tissue swelling in the left groin, one patient had a left axillary soft tissue lump and one patient presented with a parotid lump. All lesions were well circumscribed and contained variably cellular and vascularized tissue composed of round to spindle cells with a patternless arrangement, scattered multinucleate giant cells and pseudovascular spaces conforming to the description of giant cell angiofibroma. Mononuclear and multinucleate tumour cells were both positive for vimentin and CD34; one tumour exhibited focal S100 protein and GFAP positivity. Both of the tumours examined by electron microscopy showed fibroblastic features, but in addition one contained cells having Schwannian features. All four patients were well without recurrent disease on follow-up (average 25 months). Conclusion: Giant cell angiofibroma shares many features with solitary fibrous tumour and giant cell fibroblastoma and shows a wider distribution than initially recognized. Rarely, Schwannian differentiation may be observed in these tumours.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2559.2001.01227.x
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  • 12
    Electronic Resource
    Electronic Resource
    Bronchial epithelial-myoepithelial carcinoma (1998)
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Histopathology 33 (1998), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2559.1998.0415f.x
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  • 13
    Electronic Resource
    Electronic Resource
    Morphological variants of plasma cell tumours (2004)
    Oxford, UK : Blackwell Science Ltd
    Histopathology 44 (2004), S. 0 
    Details
    ISSN: 1365-2559
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Banerjee S S, Verma S & Shanks J H 
(2004) Histopathology44, 2–8 
Morphological variants of plasma cell tumours
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2559.2004.01763.x
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  • 14
    Electronic Resource
    Electronic Resource
    Effects of buffered media upon growth and alkaloid production of Catharanthus roseus hairy roots (2000)
    Springer
    Applied microbiology and biotechnology 53 (2000), S. 262-265 
    Details
    ISSN: 1432-0614
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract The influence of buffered media upon the growth and alkaloid productivity of Catharanthus roseus hairy root culture was examined. As expected, the buffers minimized shifts in the pH of the media and had slightly negative effects upon growth. The growth of the hairy roots remained optimal in unbuffered media. The specific yield of lochnericine was significantly lower in response to the addition of buffers, while tabersonine was significantly higher. In contrast, the specific yields of ajmalicine, serpentine, and hörhammericine remained unchanged.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002530050018
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  • 15
    Electronic Resource
    Electronic Resource
    General tachyon absorption by Kerr-Newman black holes: Thermodynamic consequences (1980)
    Springer
    General relativity and gravitation 12 (1980), S. 1029-1034 
    Details
    ISSN: 1572-9532
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Following the analyses of B. Carter and J. V. Narlikar, the nature of the incomplete, spacelike trajectories about a charged, rotating black hole is described. The study concentrates on those paths which a charged tachyon would follow, incident from off the equatorial plane (on whichθ=π/2). The effect of the absorption upon the black hole is calculated and it is concluded that forπ i ≠π/2 only certain charged tachyons will reduce its entropy. However, a sustained bombardment by such particles could cause the singularity to be exposed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00768928
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  • 16
    Electronic Resource
    Electronic Resource
    31P NMR and 13C NMR studies of recombinant Saccharomyces cerevisiae with altered glucose phosphorylation activities (1991)
    Springer
    Bioprocess and biosystems engineering 6 (1991), S. 273-284 
    Details
    ISSN: 1432-0797
    Source: Springer Online Journal Archives 1860-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: Abstract Manipulation of cellular metabolism to maximize the yield and rate of formation of desired products may be achieved through genetic modification. Batch fermentations utilizing glucose as a carbon source were performed for three recombinant strains of Saccharomyces cerevisiae in which the glucose phosphorylation step was altered by mutation and genetic engineering. The host strain (hxk1 hxk2 glk) is unable to grow on glucose or fructose; the three plasmids investigated expressed hexokinase PI, hexokinase PII, or glucokinase, respectively, enabling more rapid glucose and fructose phosphorylation in vivo than that provided by wild-type yeast. Intracellular metabolic state variables were determined by 31P NMR measurements of in vivo fermentations under nongrowth conditions for high cell density suspensions. Glucose consumption, ethanol and glycerol production, and polysaccharide formation were determined by 13C NMR measurements under the same experimental conditions as used in the 31P NMR measurements. The trends observed in ethanol yields for the strains under growth conditions were mimicked in the nongrowth NMR conditions. Only the strain with hexokinase PI had higher rates of glucose consumption and ethanol production in comparison to healthy diploid strains in the literature. The hexokinase PII strain drastically underutilized its glucose-phosphorylating capacity. A regulation difference in the use of magnesium-free ATP for this strain could be a possible explanation. Differences in ATP levels and cytoplasmic pH values among the strains were observed that could not have been foreseen. However, cytoplasmic pH values do not account for the differences observed among in vivo and in vitro glucose phosphorylation activities of the three recombinant strains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00369557
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  • 17
    Electronic Resource
    Electronic Resource
    Measurement of Acoustic Transients During Pulsed Holmium:YAG Laser Ablation of Cadaveric Human Temporal Bone (2000)
    Springer
    Lasers in medical science 15 (2000), S. 2-5 
    Details
    ISSN: 1435-604X
    Keywords: Keywords:Ear; Holmium:YAG laser; Laser tissue effects; Photoacoustic injury; Stapedotomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Physics , Technology
    Notes: Abstract. Pulsed infrared (IR) and ultraviolet (UV) lasers have been suggested for use in middle ear surgery due to potential fiberoptic delivery, decreased thermal trauma and precise ablation characteristics. Although attention has been focused on the thermal and photoacoustic events that occur during pulsed laser ablation of hard tissue, there are few studies which evaluate the acoustic energy generated from these devices from an audiological standpoint. In this study, the mastoid cavities of cadaveric human temporal bones were irradiated with a holmium: yttrium aluminium garnet (Ho:YAG) laser (λ=2.12 µm) using the following parameters: 5, 10, and 15 Hz pulse repetition rate and 1, 2, 4, 6, 8, and 10 W average power. During ablation, acoustic measurements were made using a sound level meter positioned 5 cm away from the target site. With each set of laser parameters, the sound intensity exceeded 85 dB (dBA scale). Peak intensities of 125 dB were measured, and a saturation effect noted above 4 W or 500 mJ/pulse. The clinical significance of these findings is discussed and the acoustical aspects of middle ear function and noise trauma are reviewed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s101030050040
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