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Analogs of oxytocin with L- and D-pentafluorophenylalanines in the second position (1977)

Kaurov, O. A. ; Smirnova, M. P.

Springer

Chemistry of natural compounds 13 (1977), S. 332-336

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ISSN: 1573-8388

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology

Notes: Summary 1. The separation of pentafluorophenylalanine into optical antipodes has been effected. 2. Two new analogs of oxytocin — [2-L-pentafluorophenylalanine]oxytocin and [2-D-pentafluorophenylalanine]oxytocin — have been synthesized and their uterotonic activities have been studied. 3. It has been shown that donor — acceptor interaction plays a fundamental role in the stimulation of the biological effect.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00573555

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