ZIB

Treffer pro Seite

Treffer 1 - 1 | 1 Treffer

Sortierung

Digitale Medien

The Drosophila Ret gene is transcribed in multiple alternatively spliced forms (2000)

Huen, D. S. ; Elsdon, M. ; Ponder, B. A. J.

Springer

Molecular genetics and genomics 264 (2000), S. 335-340

zur Merkliste hinzufügen auf der Merkliste

Details

ISSN: 1617-4623

Schlagwort(e): Drosophila c-ret Receptor tyrosine kinase Alternative splicing

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Abstract. We have cloned and sequenced the 5' and 3' ends of the Drosophila homolog of the vertebrate c-ret gene, Ret, and have derived from it the predicted protein sequence of Ret. The extracellular domain of Ret is very widely diverged from that of its vertebrate counterparts but the cadherin motif present in vertebrate c-ret proteins can also be discerned in Ret. As with the vertebrate gene, multiple splice variants were detected at the 5'-end of Ret, one of which inserts an exon with a protein-terminating frameshift into the cDNA. In contrast to human c-ret, which may vary its signalling specificity by using splicing-derived, alternative C-terminal sequences, Ret cDNAs showed no variation at their 3'-ends.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/s004380000327

Permalink

Bibliothek	Standort	Signatur	Band/Heft/Jahr	Verfügbarkeit

Andere fanden auch interessant ...

Artikel (Nationallizenzen)

Volltext

Treffer 1 - 1 | 1 Treffer